St. Louis Cardinals Lead Cincinnati Reds 4-1 in Head-to-Head Matchups (2026)

MLB2-3-0 ATS (40%)Updated June 7, 2026

The Cincinnati Reds are 1-4 against the St. Louis Cardinals in 2026 in head-to-head matchups, going 2-3-0 ATS (40% cover rate) with -37.55% ROI. Games average 10.8 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official MLB box scores.

See methodology.

Reds vs Cardinals Betting Record — 2026

Against the Spread

2-3-0

Win %

40%

ROI

-37.55%

Units

-1.9

Moneyline

1-4-0

Win %

20%

ROI

-62.46%

Units

-3.1

Over Rate

3-2-0

Win %

60%

ROI

+12.76%

Units

+0.6

From the Other Side — Cardinals vs Reds

Against the Spread

3-2-0

Win %

60%

ROI

+43.8%

Units

+2.2

Moneyline

4-1-0

Win %

80%

ROI

+41.71%

Units

+2.1

Over Rate

3-2-0

Win %

60%

ROI

+12.76%

Units

+0.6

Venue Splits

Reds Home

1-1-0 ATS

50% • -20.76%

1-1-0 ML (50%)

Cardinals Home

2-1-0 ATS

66.67% • +57.67%

3-0-0 ML (100%)

Scoring Averages

Reds

3.8

PPG

allowed

Total

10.8

Avg

games

Cardinals

PPG

3.8

allowed

Recent Matchups (2026)

Date	Matchup	Score	Spread	ATS	ML	O/U
06/072026-06-07	Reds @ Cardinals	L 5-3	-1.5	✗	L	U
06/062026-06-06	Reds @ Cardinals	L 6-5	-1.5	✓	L	O
06/052026-06-05	Reds @ Cardinals	L 10-3	-1.5	✗	L	O
05/232026-05-23	Cardinals @ Reds	W 7-6	-1.5	✓	W	O
05/232026-05-23	Cardinals @ Reds	L 1-8	-1.5	✗	L	U

Frequently Asked Questions

What is the Cincinnati Reds vs St. Louis Cardinals 2026 record?

The Cincinnati Reds are 1-4 against the St. Louis Cardinals in 2026 in head-to-head matchups.

What is the Cincinnati Reds ATS record vs the St. Louis Cardinals?

The Cincinnati Reds are 2-3-0 against the spread vs the St. Louis Cardinals in 2026 on DraftKings, with -37.55% ROI.

Do Cincinnati Reds vs St. Louis Cardinals games go over or under?

Cincinnati Reds vs St. Louis Cardinals games average 10.8 total points in 2026. The Over has hit 60% of the time.

More Reds Matchups

vs Cubs

vs Brewers

vs Pirates

See from Cardinals perspective

Head-to-head betting record for Cincinnati Reds vs St. Louis Cardinals in the 2026 season on LineTerminal. The Reds are 1-4 straight up against the Cardinals and 2-3-0 against the spread (40% cover rate, -37.55% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.