St. Louis Cardinals Lead Cincinnati Reds 12-7 in Head-to-Head Matchups (2022)

MLB10-9-0 ATS (52.63%)Data through 2022-09-18

Reds vs Cardinals Betting Record — 2022

Against the Spread
10-9-0
Win %
52.63%
ROI
+0.86%
Units
+0.2
Moneyline
7-12-0
Win %
36.84%
ROI
-2.37%
Units
-0.5
Over Rate
7-12-0
Win %
36.84%
ROI
-29.3%
Units
-5.6

From the Other Side — Cardinals vs Reds

Against the Spread
9-10-0
Win %
47.37%
ROI
+0.1%
Units
+0.0
Moneyline
12-7-0
Win %
63.16%
ROI
+0.27%
Units
+0.1
Over Rate
7-12-0
Win %
36.84%
ROI
-29.3%
Units
-5.6

Venue Splits

Reds Home
4-5-0 ATS
44.44% • -14.87%
4-5-0 ML (44.44%)
Cardinals Home
4-6-0 ATS
40% • -11.3%
7-3-0 ML (70%)

Scoring Averages

Reds
3.4
PPG
4.6
allowed
Total
8.1
Avg
19
games
Cardinals
4.6
PPG
3.4
allowed

Recent Matchups (2022)

DateScoreATSMLO/U
09/18W 0-3WU
09/17L 5-1LU
09/17L 1-0LU
09/16L 6-5LO
09/15W 2-3WU
08/31L 3-5LU
08/30W 5-1WU
08/29L 4-13LO
07/24W 6-3WU
07/23L 3-6LU
07/22W 9-5WO
07/16L 11-3LO
07/15L 7-3LO
06/12W 6-7WO
06/11L 5-4LO
06/10L 2-0LU
04/24W 4-1WU
04/23L 0-5LU
04/22L 2-4LU

Frequently Asked Questions

What is the Cincinnati Reds vs St. Louis Cardinals all-time record?
The Cincinnati Reds are 7-12 against the St. Louis Cardinals in 2022 in head-to-head matchups.
What is the Cincinnati Reds ATS record vs the St. Louis Cardinals?
The Cincinnati Reds are 10-9-0 against the spread vs the St. Louis Cardinals in 2022 on DraftKings, with +0.86% ROI.
Do Cincinnati Reds vs St. Louis Cardinals games go over or under?
Cincinnati Reds vs St. Louis Cardinals games average 8.1 total points in 2022. The Over has hit 36.84% of the time.

More Reds Matchups

Head-to-head betting record for Cincinnati Reds vs St. Louis Cardinals in the 2022 season on LineTerminal. The Reds are 7-12 straight up against the Cardinals and 10-9-0 against the spread (52.63% cover rate, +0.86% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

LineTerminal

AI-powered betting intelligence for NBA, NHL, MLB, and NCAAB.

LineTerminal provides sports data and analytics for informational and entertainment purposes only. LineTerminal does not accept, place, or facilitate bets or wagers of any kind. Odds data is sourced from third-party providers and may not reflect exact lines at every sportsbook. Past performance does not guarantee future results. Sports betting involves risk — never wager more than you can afford to lose.

If you or someone you know has a gambling problem, call 1-800-MY-RESET (National Problem Gambling Helpline) or visit ncpgambling.org. Must be 21+ in most jurisdictions. Please gamble responsibly.

© 2026 LineTerminal. All rights reserved.