St. Louis Cardinals Lead Cincinnati Reds 54-43 in Head-to-Head Matchups

MLB42-36-0 ATS (53.85%)

The Cincinnati Reds are 43-54 against the St. Louis Cardinals in head-to-head matchups, going 42-36-0 ATS (53.85% cover rate) with +1.56% ROI. Games average 8.8 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official MLB box scores.

See methodology.

Reds vs Cardinals Betting Record

Against the Spread
42-36-0
Win %
53.85%
ROI
+1.56%
Units
+1.2
Moneyline
41-53-0
Win %
43.62%
ROI
-8.62%
Units
-8.1
Over Rate
33-45-0
Win %
42.31%
ROI
-19.3%
Units
-15.1

From the Other Side — Cardinals vs Reds

Against the Spread
36-42-0
Win %
46.15%
ROI
-9.81%
Units
-7.7
Moneyline
53-41-0
Win %
56.38%
ROI
+4.46%
Units
+4.2
Over Rate
33-45-0
Win %
42.31%
ROI
-19.3%
Units
-15.1

Venue Splits

Reds Home
21-19-0 ATS
52.5% • -1.42%
20-23-0 ML (46.51%)
Cardinals Home
17-21-0 ATS
44.74% • -9.1%
30-21-0 ML (58.82%)

Scoring Averages

Reds
4.2
PPG
4.6
allowed
Total
8.8
Avg
97
games
Cardinals
4.6
PPG
4.2
allowed

Recent Matchups

DateScoreATSMLO/U
08/20L 9-10LO
08/19W 5-4WO
08/18L 0-3LU
08/17W 6-5WO
08/17L 1-2LU
07/26W 3-5WU
07/25L 7-0LU
07/24W 2-4WU
06/07L 5-3LU
06/06L 6-5LO
06/05L 10-3LO
05/23L 1-8LU
05/23W 7-6WO
09/17W 2-6WU
09/16L 3-0LU
09/15W 6-11WO
08/31W 7-4WO
08/30L 2-4LU
08/29L 5-7LO
06/22W 1-4WU

Frequently Asked Questions

What is the Cincinnati Reds vs St. Louis Cardinals all-time record?
The Cincinnati Reds are 43-54 against the St. Louis Cardinals in head-to-head matchups.
What is the Cincinnati Reds ATS record vs the St. Louis Cardinals?
The Cincinnati Reds are 42-36-0 against the spread vs the St. Louis Cardinals on DraftKings, with +1.56% ROI.
Do Cincinnati Reds vs St. Louis Cardinals games go over or under?
Cincinnati Reds vs St. Louis Cardinals games average 8.8 total points. The Over has hit 42.31% of the time.

More Reds Matchups

Head-to-head betting record for Cincinnati Reds vs St. Louis Cardinals on LineTerminal. The Reds are 43-54 straight up against the Cardinals and 42-36-0 against the spread (53.85% cover rate, +1.56% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

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