St. Louis Cardinals Lead Cincinnati Reds 46-38 in Head-to-Head Matchups

MLB30-35-0 ATS (46.15%)Data through 2025-09-17

Cardinals vs Reds Betting Record

Against the Spread
30-35-0
Win %
46.15%
ROI
-11.19%
Units
-7.3
Moneyline
45-36-0
Win %
55.56%
ROI
+2.98%
Units
+2.4
Over Rate
27-38-0
Win %
41.54%
ROI
-20.88%
Units
-13.6

From the Other Side — Reds vs Cardinals

Against the Spread
35-30-0
Win %
53.85%
ROI
+4.84%
Units
+3.1
Moneyline
36-45-0
Win %
44.44%
ROI
-6.32%
Units
-5.1
Over Rate
27-38-0
Win %
41.54%
ROI
-20.88%
Units
-13.6

Venue Splits

Cardinals Home
14-18-0 ATS
43.75% • -11.72%
26-19-0 ML (57.78%)
Reds Home
17-16-0 ATS
51.52% • +0.06%
17-19-0 ML (47.22%)

Scoring Averages

Cardinals
4.5
PPG
4.3
allowed
Total
8.8
Avg
84
games
Reds
4.3
PPG
4.5
allowed

Recent Matchups

DateScoreATSMLO/U
09/17L 2-6LU
09/16W 3-0WU
09/15L 6-11LO
08/31L 7-4LO
08/30W 2-4WU
08/29W 5-7WO
06/22L 1-4LU
06/21W 6-5WO
06/20W 6-1WU
05/01L 9-1LO
04/30W 0-6WU
04/30W 1-9WO
04/28L 3-1LU
09/12W 6-1WU
09/11W 2-1WU
09/10L 0-3LU
08/14L 9-2LO
08/13L 4-1LU
08/12L 6-1LU
06/30W 2-0WU

Frequently Asked Questions

What is the St. Louis Cardinals vs Cincinnati Reds all-time record?
The St. Louis Cardinals are 46-38 against the Cincinnati Reds in head-to-head matchups.
What is the St. Louis Cardinals ATS record vs the Cincinnati Reds?
The St. Louis Cardinals are 30-35-0 against the spread vs the Cincinnati Reds on DraftKings, with -11.19% ROI.
Do St. Louis Cardinals vs Cincinnati Reds games go over or under?
St. Louis Cardinals vs Cincinnati Reds games average 8.8 total points. The Over has hit 41.54% of the time.

More Cardinals Matchups

Head-to-head betting record for St. Louis Cardinals vs Cincinnati Reds on LineTerminal. The Cardinals are 46-38 straight up against the Reds and 30-35-0 against the spread (46.15% cover rate, -11.19% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

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