St. Louis Cardinals Lead Chicago Cubs 45-43 in Head-to-Head Matchups

MLB35-38-0 ATS (47.95%)

The St. Louis Cardinals are 45-43 against the Chicago Cubs in head-to-head matchups, going 35-38-0 ATS (47.95% cover rate) with -10.28% ROI. Games average 8.6 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official MLB box scores.

See methodology.

Cardinals vs Cubs Betting Record

Against the Spread
35-38-0
Win %
47.95%
ROI
-10.28%
Units
-7.5
Moneyline
45-42-0
Win %
51.72%
ROI
-3.19%
Units
-2.8
Over Rate
35-34-4
Win %
50.72%
ROI
-3.28%
Units
-2.3

From the Other Side — Cubs vs Cardinals

Against the Spread
38-35-0
Win %
52.05%
ROI
-0.11%
Units
-0.1
Moneyline
42-45-0
Win %
48.28%
ROI
-7.43%
Units
-6.5
Over Rate
35-34-4
Win %
50.72%
ROI
-3.28%
Units
-2.3

Venue Splits

Cardinals Home
18-19-0 ATS
48.65% • -8.83%
23-18-0 ML (56.1%)
Cubs Home
19-17-0 ATS
52.78% • +1.89%
24-22-0 ML (52.17%)

Scoring Averages

Cardinals
4.2
PPG
4.4
allowed
Total
8.6
Avg
88
games
Cubs
4.4
PPG
4.2
allowed

Recent Matchups

DateScoreATSMLO/U
07/05L 6-4LO
07/04W 0-3WU
07/03W 1-17WO
05/31W 5-1WU
05/30L 1-6LU
05/29W 6-5WO
09/28L 2-0LU
09/27L 7-3LO
09/26L 12-1LO
08/10W 3-2WU
08/09L 1-9LO
08/08W 5-0WU
07/06L 11-0LO
07/05W 6-8WO
07/04L 11-3LO
06/26L 0-3LU
06/25L 0-8LU
06/24W 8-7WO
06/23W 8-2WO
08/04L 6-2LU

Frequently Asked Questions

What is the St. Louis Cardinals vs Chicago Cubs all-time record?
The St. Louis Cardinals are 45-43 against the Chicago Cubs in head-to-head matchups.
What is the St. Louis Cardinals ATS record vs the Chicago Cubs?
The St. Louis Cardinals are 35-38-0 against the spread vs the Chicago Cubs on DraftKings, with -10.28% ROI.
Do St. Louis Cardinals vs Chicago Cubs games go over or under?
St. Louis Cardinals vs Chicago Cubs games average 8.6 total points. The Over has hit 50.72% of the time.

More Cardinals Matchups

Head-to-head betting record for St. Louis Cardinals vs Chicago Cubs on LineTerminal. The Cardinals are 45-43 straight up against the Cubs and 35-38-0 against the spread (47.95% cover rate, -10.28% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

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