St. Louis Cardinals Lead Chicago Cubs 45-43 in Head-to-Head Matchups

MLB38-35-0 ATS (52.05%)

The Chicago Cubs are 43-45 against the St. Louis Cardinals in head-to-head matchups, going 38-35-0 ATS (52.05% cover rate) with -0.11% ROI. Games average 8.6 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official MLB box scores.

See methodology.

Cubs vs Cardinals Betting Record

Against the Spread
38-35-0
Win %
52.05%
ROI
-0.11%
Units
-0.1
Moneyline
42-45-0
Win %
48.28%
ROI
-7.43%
Units
-6.5
Over Rate
35-34-4
Win %
50.72%
ROI
-3.28%
Units
-2.3

From the Other Side — Cardinals vs Cubs

Against the Spread
35-38-0
Win %
47.95%
ROI
-10.28%
Units
-7.5
Moneyline
45-42-0
Win %
51.72%
ROI
-3.19%
Units
-2.8
Over Rate
35-34-4
Win %
50.72%
ROI
-3.28%
Units
-2.3

Venue Splits

Cubs Home
19-17-0 ATS
52.78% • +1.89%
24-22-0 ML (52.17%)
Cardinals Home
18-19-0 ATS
48.65% • -8.83%
23-18-0 ML (56.1%)

Scoring Averages

Cubs
4.4
PPG
4.2
allowed
Total
8.6
Avg
88
games
Cardinals
4.2
PPG
4.4
allowed

Recent Matchups

DateScoreATSMLO/U
07/05W 6-4WO
07/04L 0-3LU
07/03L 1-17LO
05/31L 5-1LU
05/30W 1-6WU
05/29L 6-5LO
09/28W 2-0WU
09/27W 7-3WO
09/26W 12-1WO
08/10L 3-2LU
08/09W 1-9WO
08/08L 5-0LU
07/06W 11-0WO
07/05L 6-8LO
07/04W 11-3WO
06/26W 0-3WU
06/25W 0-8WU
06/24L 8-7LO
06/23L 8-2LO
08/04W 6-2WU

Frequently Asked Questions

What is the Chicago Cubs vs St. Louis Cardinals all-time record?
The Chicago Cubs are 43-45 against the St. Louis Cardinals in head-to-head matchups.
What is the Chicago Cubs ATS record vs the St. Louis Cardinals?
The Chicago Cubs are 38-35-0 against the spread vs the St. Louis Cardinals on DraftKings, with -0.11% ROI.
Do Chicago Cubs vs St. Louis Cardinals games go over or under?
Chicago Cubs vs St. Louis Cardinals games average 8.6 total points. The Over has hit 50.72% of the time.

More Cubs Matchups

Head-to-head betting record for Chicago Cubs vs St. Louis Cardinals on LineTerminal. The Cubs are 43-45 straight up against the Cardinals and 38-35-0 against the spread (52.05% cover rate, -0.11% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

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