St. Louis Cardinals Lead Pittsburgh Pirates 48-37 in Head-to-Head Matchups

MLB31-37-0 ATS (45.59%)Data through 2025-08-28

Cardinals vs Pirates Betting Record

Against the Spread
31-37-0
Win %
45.59%
ROI
-8.37%
Units
-5.7
Moneyline
48-37-0
Win %
56.47%
ROI
-5.12%
Units
-4.3
Over Rate
28-35-5
Win %
44.44%
ROI
-14.3%
Units
-9.0

From the Other Side — Pirates vs Cardinals

Against the Spread
37-31-0
Win %
54.41%
ROI
-2.42%
Units
-1.6
Moneyline
37-48-0
Win %
43.53%
ROI
-2.6%
Units
-2.2
Over Rate
28-35-5
Win %
44.44%
ROI
-14.3%
Units
-9.0

Venue Splits

Cardinals Home
19-15-0 ATS
55.88% • +15.53%
27-18-0 ML (60%)
Pirates Home
22-12-0 ATS
64.71% • +15.14%
19-21-0 ML (47.5%)

Scoring Averages

Cardinals
4.3
PPG
3.7
allowed
Total
8.1
Avg
85
games
Pirates
3.7
PPG
4.3
allowed

Recent Matchups

DateScoreATSMLO/U
08/28W 4-1WU
08/27L 1-2LU
08/26L 3-8LO
08/25W 7-6WO
07/02L 5-0LU
07/01L 1-0LU
06/30L 7-0LU
05/07W 5-0WU
05/06W 2-1WU
05/05W 6-3WO
04/09L 2-1LU
04/08W 3-5WO
04/07L 8-4LO
09/19L 2-3LU
09/18W 10-5WO
09/17W 3-1WU
09/16W 4-0WU
07/24L 5-0LU
07/23W 1-2WU
07/22L 2-1LU

Frequently Asked Questions

What is the St. Louis Cardinals vs Pittsburgh Pirates all-time record?
The St. Louis Cardinals are 48-37 against the Pittsburgh Pirates in head-to-head matchups.
What is the St. Louis Cardinals ATS record vs the Pittsburgh Pirates?
The St. Louis Cardinals are 31-37-0 against the spread vs the Pittsburgh Pirates on DraftKings, with -8.37% ROI.
Do St. Louis Cardinals vs Pittsburgh Pirates games go over or under?
St. Louis Cardinals vs Pittsburgh Pirates games average 8.1 total points. The Over has hit 44.44% of the time.

More Cardinals Matchups

Head-to-head betting record for St. Louis Cardinals vs Pittsburgh Pirates on LineTerminal. The Cardinals are 48-37 straight up against the Pirates and 31-37-0 against the spread (45.59% cover rate, -8.37% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

LineTerminal

AI-powered betting intelligence for NBA, NHL, MLB, and NCAAB.

LineTerminal provides sports data and analytics for informational and entertainment purposes only. LineTerminal does not accept, place, or facilitate bets or wagers of any kind. Odds data is sourced from third-party providers and may not reflect exact lines at every sportsbook. Past performance does not guarantee future results. Sports betting involves risk — never wager more than you can afford to lose.

If you or someone you know has a gambling problem, call 1-800-MY-RESET (National Problem Gambling Helpline) or visit ncpgambling.org. Must be 21+ in most jurisdictions. Please gamble responsibly.

© 2026 LineTerminal. All rights reserved.