CardinalsAway1
PiratesHome2Run lineMissFav -1.5
MoneylineWin
TotalUnder7
MLB · Head to head
Pirates vs Cardinals
All recorded seasonsLast meeting Sep 24, 2026
Betting comparison
All seasons
Pirates
81 bets41-40-0Wins · Losses · Pushes
- Win rate
- 50.62%
- ROI
- -7.22%
- Units
- -5.84u
Cardinals
81 bets40-41-0Wins · Losses · Pushes
- Win rate
- 49.38%
- ROI
- -3.99%
- Units
- -3.23u
Closing lines · Flat 1u per bet · Methodology
Scoring per game
Average runsPirates3.8
Cardinals4.3
Combined8.1
Recent meetings
Bet results from the Pirates perspective. Spread values show the favorite’s closing line.
CardinalsAway1PiratesHome2CardinalsAway5PiratesHome1Run lineMissFav -1.5
MoneylineLoss
TotalUnder7.5
CardinalsAway0PiratesHome2Run lineCoverFav -1.5
MoneylineWin
TotalUnder7
PiratesAway5CardinalsHome4Run lineMissFav -1.5
MoneylineWin
TotalOver7.5
PiratesAway6CardinalsHome2Run lineCoverFav -1.5
MoneylineWin
TotalPush8
More Pirates matchups
About this matchup
What is the Pittsburgh Pirates vs St. Louis Cardinals all-time record?
The Pittsburgh Pirates are 43-55 against the St. Louis Cardinals in head-to-head matchups.
What is the Pittsburgh Pirates ATS record vs the St. Louis Cardinals?
The Pittsburgh Pirates are 41-40-0 against the spread vs the St. Louis Cardinals on DraftKings, with -7.22% ROI.
Do Pittsburgh Pirates vs St. Louis Cardinals games go over or under?
Pittsburgh Pirates vs St. Louis Cardinals games average 8.1 total runs. The Over has hit 45.33% of the time.