St. Louis Cardinals Lead Pittsburgh Pirates 48-37 in Head-to-Head Matchups

MLB37-31-0 ATS (54.41%)Data through 2025-08-28

Pirates vs Cardinals Betting Record

Against the Spread
37-31-0
Win %
54.41%
ROI
-2.42%
Units
-1.6
Moneyline
37-48-0
Win %
43.53%
ROI
-2.6%
Units
-2.2
Over Rate
28-35-5
Win %
44.44%
ROI
-14.3%
Units
-9.0

From the Other Side — Cardinals vs Pirates

Against the Spread
31-37-0
Win %
45.59%
ROI
-8.37%
Units
-5.7
Moneyline
48-37-0
Win %
56.47%
ROI
-5.12%
Units
-4.3
Over Rate
28-35-5
Win %
44.44%
ROI
-14.3%
Units
-9.0

Venue Splits

Pirates Home
22-12-0 ATS
64.71% • +15.14%
19-21-0 ML (47.5%)
Cardinals Home
19-15-0 ATS
55.88% • +15.53%
27-18-0 ML (60%)

Scoring Averages

Pirates
3.7
PPG
4.3
allowed
Total
8.1
Avg
85
games
Cardinals
4.3
PPG
3.7
allowed

Recent Matchups

DateScoreATSMLO/U
08/28L 4-1LU
08/27W 1-2WU
08/26W 3-8WO
08/25L 7-6LO
07/02W 5-0WU
07/01W 1-0WU
06/30W 7-0WU
05/07L 5-0LU
05/06L 2-1LU
05/05L 6-3LO
04/09W 2-1WU
04/08L 3-5LO
04/07W 8-4WO
09/19W 2-3WU
09/18L 10-5LO
09/17L 3-1LU
09/16L 4-0LU
07/24W 5-0WU
07/23L 1-2LU
07/22W 2-1WU

Frequently Asked Questions

What is the Pittsburgh Pirates vs St. Louis Cardinals all-time record?
The Pittsburgh Pirates are 37-48 against the St. Louis Cardinals in head-to-head matchups.
What is the Pittsburgh Pirates ATS record vs the St. Louis Cardinals?
The Pittsburgh Pirates are 37-31-0 against the spread vs the St. Louis Cardinals on DraftKings, with -2.42% ROI.
Do Pittsburgh Pirates vs St. Louis Cardinals games go over or under?
Pittsburgh Pirates vs St. Louis Cardinals games average 8.1 total points. The Over has hit 44.44% of the time.

More Pirates Matchups

Head-to-head betting record for Pittsburgh Pirates vs St. Louis Cardinals on LineTerminal. The Pirates are 37-48 straight up against the Cardinals and 37-31-0 against the spread (54.41% cover rate, -2.42% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

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