Los Angeles Rams Lead San Francisco 49ers 2-0 in Head-to-Head Matchups (2024-25)

NFL0-2-0 ATS (0%)Updated December 12, 2024

The San Francisco 49ers are 0-2 against the Los Angeles Rams in 2024-25 in head-to-head matchups, going 0-2-0 ATS (0% cover rate) with -100% ROI. Games average 34.5 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official NFL box scores.

See methodology.

49ers vs Rams Betting Record — 2024-25

Against the Spread

0-2-0

Win %

ROI

-100%

Units

-2.0

Moneyline

0-2-0

Win %

ROI

-100%

Units

-2.0

Over Rate

1-1-0

Win %

50%

ROI

-3.7%

Units

-0.1

From the Other Side — Rams vs 49ers

Against the Spread

2-0-0

Win %

100%

ROI

+87.02%

Units

+1.7

Moneyline

2-0-0

Win %

100%

ROI

+170%

Units

+3.4

Over Rate

1-1-0

Win %

50%

ROI

-3.7%

Units

-0.1

Venue Splits

49ers Home

0-1-0 ATS

0% • -100%

0-1-0 ML (0%)

Rams Home

1-0-0 ATS

100% • +89.29%

1-0-0 ML (100%)

Scoring Averages

49ers

PPG

19.5

allowed

Total

34.5

Avg

games

Rams

19.5

PPG

allowed

Recent Matchups (2024-25)

Date	Matchup	Score	Spread	ATS	ML	O/U
12/122024-12-12	Rams @ 49ers	L 6-12	-3	✗	L	U
09/222024-09-22	49ers @ Rams	L 27-24	-6	✗	L	O

Frequently Asked Questions

What is the San Francisco 49ers vs Los Angeles Rams 2024-25 record?

The San Francisco 49ers are 0-2 against the Los Angeles Rams in 2024-25 in head-to-head matchups.

What is the San Francisco 49ers ATS record vs the Los Angeles Rams?

The San Francisco 49ers are 0-2-0 against the spread vs the Los Angeles Rams in 2024-25 on DraftKings, with -100% ROI.

Do San Francisco 49ers vs Los Angeles Rams games go over or under?

San Francisco 49ers vs Los Angeles Rams games average 34.5 total points in 2024-25. The Over has hit 50% of the time.

More 49ers Matchups

vs Cardinals

vs Seahawks

See from Rams perspective

Head-to-head betting record for San Francisco 49ers vs Los Angeles Rams in the 2024-25 season on LineTerminal. The 49ers are 0-2 straight up against the Rams and 0-2-0 against the spread (0% cover rate, -100% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.