St. Louis Cardinals Lead Pittsburgh Pirates 5-2 in Head-to-Head Matchups (2026)

MLB5-2-0 ATS (71.43%)

The St. Louis Cardinals are 5-2 against the Pittsburgh Pirates in 2026 in head-to-head matchups, going 5-2-0 ATS (71.43% cover rate) with +30.71% ROI. Games average 11.1 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official MLB box scores.

See methodology.

Cardinals vs Pirates Betting Record — 2026

Against the Spread
5-2-0
Win %
71.43%
ROI
+30.71%
Units
+2.1
Moneyline
5-2-0
Win %
71.43%
ROI
+60.99%
Units
+4.3
Over Rate
5-2-0
Win %
71.43%
ROI
+36.63%
Units
+2.6

From the Other Side — Pirates vs Cardinals

Against the Spread
2-5-0
Win %
28.57%
ROI
-29.14%
Units
-2.0
Moneyline
2-5-0
Win %
28.57%
ROI
-45.92%
Units
-3.2
Over Rate
5-2-0
Win %
71.43%
ROI
+36.63%
Units
+2.6

Venue Splits

Cardinals Home
1-2-0 ATS
33.33% • -47.83%
1-2-0 ML (33.33%)
Pirates Home
0-4-0 ATS
0% • -100%
0-4-0 ML (0%)

Scoring Averages

Cardinals
5.9
PPG
5.3
allowed
Total
11.1
Avg
7
games
Pirates
5.3
PPG
5.9
allowed

Recent Matchups (2026)

DateScoreATSMLO/U
05/21L 2-6LO
05/20L 0-7LU
05/19W 9-6WO
04/30W 5-10WO
04/29W 4-5WO
04/28W 7-11WO
04/27W 2-4WU

Frequently Asked Questions

What is the St. Louis Cardinals vs Pittsburgh Pirates 2026 record?
The St. Louis Cardinals are 5-2 against the Pittsburgh Pirates in 2026 in head-to-head matchups.
What is the St. Louis Cardinals ATS record vs the Pittsburgh Pirates?
The St. Louis Cardinals are 5-2-0 against the spread vs the Pittsburgh Pirates in 2026 on DraftKings, with +30.71% ROI.
Do St. Louis Cardinals vs Pittsburgh Pirates games go over or under?
St. Louis Cardinals vs Pittsburgh Pirates games average 11.1 total points in 2026. The Over has hit 71.43% of the time.

More Cardinals Matchups

Head-to-head betting record for St. Louis Cardinals vs Pittsburgh Pirates in the 2026 season on LineTerminal. The Cardinals are 5-2 straight up against the Pirates and 5-2-0 against the spread (71.43% cover rate, +30.71% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

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