St. Louis Cardinals Lead Pittsburgh Pirates 5-2 in Head-to-Head Matchups (2026)

MLB2-5-0 ATS (28.57%)

The Pittsburgh Pirates are 2-5 against the St. Louis Cardinals in 2026 in head-to-head matchups, going 2-5-0 ATS (28.57% cover rate) with -29.14% ROI. Games average 11.1 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official MLB box scores.

See methodology.

Pirates vs Cardinals Betting Record — 2026

Against the Spread
2-5-0
Win %
28.57%
ROI
-29.14%
Units
-2.0
Moneyline
2-5-0
Win %
28.57%
ROI
-45.92%
Units
-3.2
Over Rate
5-2-0
Win %
71.43%
ROI
+36.63%
Units
+2.6

From the Other Side — Cardinals vs Pirates

Against the Spread
5-2-0
Win %
71.43%
ROI
+30.71%
Units
+2.1
Moneyline
5-2-0
Win %
71.43%
ROI
+60.99%
Units
+4.3
Over Rate
5-2-0
Win %
71.43%
ROI
+36.63%
Units
+2.6

Venue Splits

Pirates Home
0-4-0 ATS
0% • -100%
0-4-0 ML (0%)
Cardinals Home
1-2-0 ATS
33.33% • -47.83%
1-2-0 ML (33.33%)

Scoring Averages

Pirates
5.3
PPG
5.9
allowed
Total
11.1
Avg
7
games
Cardinals
5.9
PPG
5.3
allowed

Recent Matchups (2026)

DateScoreATSMLO/U
05/21W 2-6WO
05/20W 0-7WU
05/19L 9-6LO
04/30L 5-10LO
04/29L 4-5LO
04/28L 7-11LO
04/27L 2-4LU

Frequently Asked Questions

What is the Pittsburgh Pirates vs St. Louis Cardinals 2026 record?
The Pittsburgh Pirates are 2-5 against the St. Louis Cardinals in 2026 in head-to-head matchups.
What is the Pittsburgh Pirates ATS record vs the St. Louis Cardinals?
The Pittsburgh Pirates are 2-5-0 against the spread vs the St. Louis Cardinals in 2026 on DraftKings, with -29.14% ROI.
Do Pittsburgh Pirates vs St. Louis Cardinals games go over or under?
Pittsburgh Pirates vs St. Louis Cardinals games average 11.1 total points in 2026. The Over has hit 71.43% of the time.

More Pirates Matchups

Head-to-head betting record for Pittsburgh Pirates vs St. Louis Cardinals in the 2026 season on LineTerminal. The Pirates are 2-5 straight up against the Cardinals and 2-5-0 against the spread (28.57% cover rate, -29.14% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

LineTerminal provides sports data and analytics for informational and entertainment purposes only. LineTerminal does not accept, place, or facilitate bets or wagers of any kind. Odds data is sourced from third-party providers and may not reflect exact lines at every sportsbook. Past performance does not guarantee future results. Sports betting involves risk — never wager more than you can afford to lose.

If you or someone you know has a gambling problem, call 1-800-MY-RESET (National Problem Gambling Helpline) or visit ncpgambling.org. Must be 21+ in most jurisdictions. Please gamble responsibly.

© 2026 LineTerminal LLC. All rights reserved.