St. Louis Cardinals Lead Cincinnati Reds 7-6 in Head-to-Head Matchups (2025)

MLB6-7-0 ATS (46.15%)Data through 2025-09-17

Cardinals vs Reds Betting Record — 2025

Against the Spread
6-7-0
Win %
46.15%
ROI
-12.58%
Units
-1.6
Moneyline
7-6-0
Win %
53.85%
ROI
+5.15%
Units
+0.7
Over Rate
6-7-0
Win %
46.15%
ROI
-11.83%
Units
-1.5

From the Other Side — Reds vs Cardinals

Against the Spread
7-6-0
Win %
53.85%
ROI
+12.72%
Units
+1.6
Moneyline
6-7-0
Win %
46.15%
ROI
-15.05%
Units
-2.0
Over Rate
6-7-0
Win %
46.15%
ROI
-11.83%
Units
-1.5

Venue Splits

Cardinals Home
2-4-0 ATS
33.33% • -31.97%
3-3-0 ML (50%)
Reds Home
3-4-0 ATS
42.86% • -19.96%
3-4-0 ML (42.86%)

Scoring Averages

Cardinals
4.3
PPG
4.2
allowed
Total
8.5
Avg
13
games
Reds
4.2
PPG
4.3
allowed

Recent Matchups (2025)

DateScoreATSMLO/U
09/17L 2-6LU
09/16W 3-0WU
09/15L 6-11LO
08/31L 7-4LO
08/30W 2-4WU
08/29W 5-7WO
06/22L 1-4LU
06/21W 6-5WO
06/20W 6-1WU
05/01L 9-1LO
04/30W 1-9WO
04/30W 0-6WU
04/28L 3-1LU

Frequently Asked Questions

What is the St. Louis Cardinals vs Cincinnati Reds all-time record?
The St. Louis Cardinals are 7-6 against the Cincinnati Reds in 2025 in head-to-head matchups.
What is the St. Louis Cardinals ATS record vs the Cincinnati Reds?
The St. Louis Cardinals are 6-7-0 against the spread vs the Cincinnati Reds in 2025 on DraftKings, with -12.58% ROI.
Do St. Louis Cardinals vs Cincinnati Reds games go over or under?
St. Louis Cardinals vs Cincinnati Reds games average 8.5 total points in 2025. The Over has hit 46.15% of the time.

More Cardinals Matchups

Head-to-head betting record for St. Louis Cardinals vs Cincinnati Reds in the 2025 season on LineTerminal. The Cardinals are 7-6 straight up against the Reds and 6-7-0 against the spread (46.15% cover rate, -12.58% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

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