Minnesota Twins Lead Cleveland Guardians 2-1 in Head-to-Head Matchups (2026)

MLB2-1-0 ATS (66.67%)Updated 13 days ago

The Cleveland Guardians are 1-2 against the Minnesota Twins in 2026 in head-to-head matchups, going 2-1-0 ATS (66.67% cover rate) with +34.85% ROI. Games average 7.3 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official MLB box scores.

See methodology.

Guardians vs Twins Betting Record — 2026

Against the Spread

2-1-0

Win %

66.67%

ROI

+34.85%

Units

+1.1

Moneyline

1-2-0

Win %

33.33%

ROI

-44.3%

Units

-1.3

Over Rate

2-1-0

Win %

66.67%

ROI

+26.45%

Units

+0.8

From the Other Side — Twins vs Guardians

Against the Spread

1-2-0

Win %

33.33%

ROI

-47.62%

Units

-1.4

Moneyline

2-1-0

Win %

66.67%

ROI

+45.67%

Units

+1.4

Over Rate

2-1-0

Win %

66.67%

ROI

+26.45%

Units

+0.8

Venue Splits

Guardians Home

2-1-0 ATS

66.67% • +34.85%

1-2-0 ML (33.33%)

Twins Home

Scoring Averages

Guardians

3.7

PPG

3.7

allowed

Total

7.3

Avg

games

Twins

3.7

PPG

3.7

allowed

Recent Matchups (2026)

Date	Matchup	Score	Spread	ATS	ML	O/U
05/102026-05-10	Twins @ Guardians	L 4-5	-1.5	✗	L	O
05/092026-05-09	Twins @ Guardians	L 1-2	-1.5	✓	L	U
05/082026-05-08	Twins @ Guardians	W 6-4	-1.5	✓	W	O

Frequently Asked Questions

What is the Cleveland Guardians vs Minnesota Twins 2026 record?

The Cleveland Guardians are 1-2 against the Minnesota Twins in 2026 in head-to-head matchups.

What is the Cleveland Guardians ATS record vs the Minnesota Twins?

The Cleveland Guardians are 2-1-0 against the spread vs the Minnesota Twins in 2026 on DraftKings, with +34.85% ROI.

Do Cleveland Guardians vs Minnesota Twins games go over or under?

Cleveland Guardians vs Minnesota Twins games average 7.3 total points in 2026. The Over has hit 66.67% of the time.

More Guardians Matchups

vs White Sox

vs Tigers

vs Royals

See from Twins perspective

Head-to-head betting record for Cleveland Guardians vs Minnesota Twins in the 2026 season on LineTerminal. The Guardians are 1-2 straight up against the Twins and 2-1-0 against the spread (66.67% cover rate, +34.85% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.