Chicago White Sox Lead Cleveland Guardians 4-3 in Head-to-Head Matchups (2026)

MLB1-6-0 ATS (14.29%)

The Cleveland Guardians are 3-4 against the Chicago White Sox in 2026 in head-to-head matchups, going 1-6-0 ATS (14.29% cover rate) with -78.12% ROI. Games average 8 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official MLB box scores.

See methodology.

Guardians vs White Sox Betting Record — 2026

Against the Spread
1-6-0
Win %
14.29%
ROI
-78.12%
Units
-5.5
Moneyline
3-4-0
Win %
42.86%
ROI
-22.06%
Units
-1.5
Over Rate
3-4-0
Win %
42.86%
ROI
-17.11%
Units
-1.2

From the Other Side — White Sox vs Guardians

Against the Spread
6-1-0
Win %
85.71%
ROI
+32.28%
Units
+2.3
Moneyline
4-3-0
Win %
57.14%
ROI
+17.45%
Units
+1.2
Over Rate
3-4-0
Win %
42.86%
ROI
-17.11%
Units
-1.2

Venue Splits

Guardians Home
1-3-0 ATS
25% • -61.7%
2-2-0 ML (50%)
White Sox Home
3-0-0 ATS
100% • +54.46%
2-1-0 ML (66.67%)

Scoring Averages

Guardians
3.9
PPG
4.1
allowed
Total
8
Avg
7
games
White Sox
4.1
PPG
3.9
allowed

Recent Matchups (2026)

DateScoreATSMLO/U
07/05L 6-7LO
07/04L 1-3LU
07/03W 4-3WU
07/02W 6-5WO
06/24W 3-4WU
06/23L 2-1LU
06/22L 6-5LO

Frequently Asked Questions

What is the Cleveland Guardians vs Chicago White Sox 2026 record?
The Cleveland Guardians are 3-4 against the Chicago White Sox in 2026 in head-to-head matchups.
What is the Cleveland Guardians ATS record vs the Chicago White Sox?
The Cleveland Guardians are 1-6-0 against the spread vs the Chicago White Sox in 2026 on DraftKings, with -78.12% ROI.
Do Cleveland Guardians vs Chicago White Sox games go over or under?
Cleveland Guardians vs Chicago White Sox games average 8 total points in 2026. The Over has hit 42.86% of the time.

More Guardians Matchups

Head-to-head betting record for Cleveland Guardians vs Chicago White Sox in the 2026 season on LineTerminal. The Guardians are 3-4 straight up against the White Sox and 1-6-0 against the spread (14.29% cover rate, -78.12% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

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