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MLB ยท Head to head

Guardians vs White Sox

Guardians43
Series wins74 games
White Sox31
All recorded seasonsLast meeting Oct 7, 2026

Betting comparison

All seasons

Guardians

74 bets
35-39-0Wins ยท Losses ยท Pushes
Win rate
47.3%
ROI
-4.94%
Units
-3.66u

White Sox

74 bets
39-35-0Wins ยท Losses ยท Pushes
Win rate
52.7%
ROI
-8.69%
Units
-6.43u

Closing lines ยท Flat 1u per bet ยท Methodology

Scoring per game

Average runs
Guardians4.3
White Sox3.7
Combined8

Recent meetings

Bet results from the Guardians perspective. Spread values show the favoriteโ€™s closing line.

GuardiansAway9
White SoxHome3
Run lineCoverFav -1.5
MoneylineWin
TotalOver7.5
White SoxAway4
GuardiansHome3
Run lineMissFav -1.5
MoneylineLoss
TotalOver6.5
White SoxAway3
GuardiansHome0
Run lineMissFav -1.5
MoneylineLoss
TotalUnder6.5
White SoxAway3
GuardiansHome6
Run lineCoverFav -1.5
MoneylineWin
TotalOver7
White SoxAway6
GuardiansHome7
Run lineMissFav -1.5
MoneylineWin
TotalOver9

About this matchup

What is the Cleveland Guardians vs Chicago White Sox all-time record?

The Cleveland Guardians are 43-31 against the Chicago White Sox in head-to-head matchups.

What is the Cleveland Guardians ATS record vs the Chicago White Sox?

The Cleveland Guardians are 35-39-0 against the spread vs the Chicago White Sox on DraftKings, with -4.94% ROI.

Do Cleveland Guardians vs Chicago White Sox games go over or under?

Cleveland Guardians vs Chicago White Sox games average 8 total runs. The Over has hit 47.95% of the time.

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