White Sox vs Guardians Betting Record
Against the Spread
27-31-0
Win %
46.55%
ROI
-16.14%
Units
-9.4
Moneyline
22-36-0
Win %
37.93%
ROI
-21.49%
Units
-12.5
Over Rate
25-32-1
Win %
43.86%
ROI
-17.39%
Units
-9.9
From the Other Side — Guardians vs White Sox
Against the Spread
31-27-0
Win %
53.45%
ROI
+8.08%
Units
+4.7
Moneyline
36-22-0
Win %
62.07%
ROI
+8.92%
Units
+5.2
Over Rate
25-32-1
Win %
43.86%
ROI
-17.39%
Units
-9.9
Venue Splits
White Sox Home
12-18-0 ATS
40% • -26.2%
12-18-0 ML (40%)
Guardians Home
13-15-0 ATS
46.43% • -2.47%
18-10-0 ML (64.29%)
Scoring Averages
White Sox
3.6
PPG
4.3
allowed
Total
7.9
Avg
58
games
Guardians
4.3
PPG
3.6
allowed
Recent Matchups
| Date | Score | ATS | ML | O/U |
|---|---|---|---|---|
| 09/142025-09-14 | L 3-2 | ✓ | L | U |
| 09/132025-09-13 | L 3-1 | ✗ | L | U |
| 09/122025-09-12 | L 4-0 | ✗ | L | U |
| 08/102025-08-10 | W 6-4 | ✓ | W | O |
| 08/092025-08-09 | L 1-3 | ✗ | L | U |
| 08/082025-08-08 | L 5-9 | ✗ | L | O |
| 07/132025-07-13 | L 5-6 | ✓ | L | O |
| 07/122025-07-12 | L 2-6 | ✗ | L | U |
| 07/112025-07-11 | L 2-4 | ✗ | L | U |
| 07/112025-07-11 | W 5-4 | ✓ | W | O |
| 04/102025-04-10 | L 6-1 | ✗ | L | U |
| 04/092025-04-09 | L 3-2 | ✓ | L | U |
| 04/082025-04-08 | L 1-0 | ✓ | L | U |
| 09/112024-09-11 | L 4-6 | ✗ | L | O |
| 09/102024-09-10 | L 0-5 | ✗ | L | U |
| 09/092024-09-09 | L 3-5 | ✗ | L | U |
| 07/042024-07-04 | L 8-4 | ✗ | L | O |
| 07/032024-07-03 | W 2-8 | ✓ | W | O |
| 07/022024-07-02 | L 7-6 | ✓ | L | O |
| 05/122024-05-12 | L 0-7 | ✗ | L | U |
Frequently Asked Questions
What is the Chicago White Sox vs Cleveland Guardians all-time record?
The Chicago White Sox are 22-36 against the Cleveland Guardians in head-to-head matchups.
What is the Chicago White Sox ATS record vs the Cleveland Guardians?
The Chicago White Sox are 27-31-0 against the spread vs the Cleveland Guardians on DraftKings, with -16.14% ROI.
Do Chicago White Sox vs Cleveland Guardians games go over or under?
Chicago White Sox vs Cleveland Guardians games average 7.9 total points. The Over has hit 43.86% of the time.

Inside Edge
