GuardiansAway9
White SoxHome3Run lineMissFav -1.5
MoneylineLoss
TotalOver7.5
MLB · Head to head
White Sox vs Guardians
All recorded seasonsLast meeting Oct 7, 2026
Betting comparison
All seasons
White Sox
74 bets39-35-0Wins · Losses · Pushes
- Win rate
- 52.7%
- ROI
- -8.69%
- Units
- -6.43u
Guardians
74 bets35-39-0Wins · Losses · Pushes
- Win rate
- 47.3%
- ROI
- -4.94%
- Units
- -3.66u
Closing lines · Flat 1u per bet · Methodology
Scoring per game
Average runsWhite Sox3.7
Guardians4.3
Combined8
Recent meetings
Bet results from the White Sox perspective. Spread values show the favorite’s closing line.
GuardiansAway9White SoxHome3White SoxAway4GuardiansHome3Run lineCoverFav -1.5
MoneylineWin
TotalOver6.5
White SoxAway3GuardiansHome0Run lineCoverFav -1.5
MoneylineWin
TotalUnder6.5
White SoxAway3GuardiansHome6Run lineMissFav -1.5
MoneylineLoss
TotalOver7
White SoxAway6GuardiansHome7Run lineCoverFav -1.5
MoneylineLoss
TotalOver9
More White Sox matchups
About this matchup
What is the Chicago White Sox vs Cleveland Guardians all-time record?
The Chicago White Sox are 31-43 against the Cleveland Guardians in head-to-head matchups.
What is the Chicago White Sox ATS record vs the Cleveland Guardians?
The Chicago White Sox are 39-35-0 against the spread vs the Cleveland Guardians on DraftKings, with -8.69% ROI.
Do Chicago White Sox vs Cleveland Guardians games go over or under?
Chicago White Sox vs Cleveland Guardians games average 8 total runs. The Over has hit 47.95% of the time.