Guardians vs Twins Betting Record
Against the Spread
33-27-0
Win %
55%
ROI
-0.01%
Units
-0.0
Moneyline
39-21-0
Win %
65%
ROI
+26.84%
Units
+16.1
Over Rate
21-37-2
Win %
36.21%
ROI
-30.17%
Units
-17.5
From the Other Side — Twins vs Guardians
Against the Spread
27-33-0
Win %
45%
ROI
-14.95%
Units
-9.0
Moneyline
21-39-0
Win %
35%
ROI
-34.35%
Units
-20.6
Over Rate
21-37-2
Win %
36.21%
ROI
-30.17%
Units
-17.5
Venue Splits
Guardians Home
14-19-0 ATS
42.42% • -26.56%
21-12-0 ML (63.64%)
Twins Home
8-19-0 ATS
29.63% • -42.48%
9-18-0 ML (33.33%)
Scoring Averages
Guardians
4.1
PPG
4
allowed
Total
8
Avg
60
games
Twins
4
PPG
4.1
allowed
Recent Matchups
| Date | Score | ATS | ML | O/U |
|---|---|---|---|---|
| 05/102026-05-10 | L 4-5 | ✗ | L | O |
| 05/092026-05-09 | L 1-2 | ✓ | L | U |
| 05/082026-05-08 | W 6-4 | ✓ | W | O |
| 09/212025-09-21 | L 6-2 | ✗ | L | U |
| 09/202025-09-20 | W 0-8 | ✓ | W | U |
| 09/202025-09-20 | W 0-6 | ✓ | W | U |
| 09/192025-09-19 | W 2-6 | ✓ | W | P |
| 08/032025-08-03 | L 4-5 | ✗ | L | O |
| 08/022025-08-02 | W 5-4 | ✗ | W | O |
| 08/012025-08-01 | W 3-2 | ✗ | W | U |
| 05/212025-05-21 | W 1-5 | ✓ | W | U |
| 05/192025-05-19 | L 6-5 | ✓ | L | O |
| 05/012025-05-01 | W 4-3 | ✓ | W | U |
| 04/302025-04-30 | W 4-2 | ✓ | W | U |
| 04/292025-04-29 | W 2-1 | ✗ | W | U |
| 04/282025-04-28 | L 1-11 | ✗ | L | O |
| 09/192024-09-19 | W 3-2 | ✓ | W | U |
| 09/182024-09-18 | W 5-4 | ✗ | W | O |
| 09/172024-09-17 | L 1-4 | ✗ | L | U |
| 09/162024-09-16 | W 4-3 | ✓ | W | U |
Frequently Asked Questions
What is the Cleveland Guardians vs Minnesota Twins all-time record?
The Cleveland Guardians are 39-21 against the Minnesota Twins in head-to-head matchups.
What is the Cleveland Guardians ATS record vs the Minnesota Twins?
The Cleveland Guardians are 33-27-0 against the spread vs the Minnesota Twins on DraftKings, with -0.01% ROI.
Do Cleveland Guardians vs Minnesota Twins games go over or under?
Cleveland Guardians vs Minnesota Twins games average 8 total points. The Over has hit 36.21% of the time.

Inside Edge
