Cleveland Guardians Lead Minnesota Twins 39-21 in Head-to-Head Matchups

MLB27-33-0 ATS (45%)

The Minnesota Twins are 21-39 against the Cleveland Guardians in head-to-head matchups, going 27-33-0 ATS (45% cover rate) with -14.95% ROI. Games average 8 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official MLB box scores.

See methodology.

Twins vs Guardians Betting Record

Against the Spread
27-33-0
Win %
45%
ROI
-14.95%
Units
-9.0
Moneyline
21-39-0
Win %
35%
ROI
-34.35%
Units
-20.6
Over Rate
21-37-2
Win %
36.21%
ROI
-30.17%
Units
-17.5

From the Other Side — Guardians vs Twins

Against the Spread
33-27-0
Win %
55%
ROI
-0.01%
Units
-0.0
Moneyline
39-21-0
Win %
65%
ROI
+26.84%
Units
+16.1
Over Rate
21-37-2
Win %
36.21%
ROI
-30.17%
Units
-17.5

Venue Splits

Twins Home
8-19-0 ATS
29.63% • -42.48%
9-18-0 ML (33.33%)
Guardians Home
14-19-0 ATS
42.42% • -26.56%
21-12-0 ML (63.64%)

Scoring Averages

Twins
4
PPG
4.1
allowed
Total
8
Avg
60
games
Guardians
4.1
PPG
4
allowed

Recent Matchups

DateScoreATSMLO/U
05/10W 4-5WO
05/09W 1-2WU
05/08L 6-4LO
09/21W 6-2WU
09/20L 0-8LU
09/20L 0-6LU
09/19L 2-6LP
08/03W 4-5WO
08/02L 5-4LO
08/01L 3-2LU
05/21L 1-5LU
05/19W 6-5WO
05/01L 4-3LU
04/30L 4-2LU
04/29L 2-1LU
04/28W 1-11WO
09/19L 3-2LU
09/18L 5-4LO
09/17W 1-4WU
09/16L 4-3LU

Frequently Asked Questions

What is the Minnesota Twins vs Cleveland Guardians all-time record?
The Minnesota Twins are 21-39 against the Cleveland Guardians in head-to-head matchups.
What is the Minnesota Twins ATS record vs the Cleveland Guardians?
The Minnesota Twins are 27-33-0 against the spread vs the Cleveland Guardians on DraftKings, with -14.95% ROI.
Do Minnesota Twins vs Cleveland Guardians games go over or under?
Minnesota Twins vs Cleveland Guardians games average 8 total points. The Over has hit 36.21% of the time.

More Twins Matchups

Head-to-head betting record for Minnesota Twins vs Cleveland Guardians on LineTerminal. The Twins are 21-39 straight up against the Guardians and 27-33-0 against the spread (45% cover rate, -14.95% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

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