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MLB ยท Head to head

Guardians vs White Sox

Guardians11
Series wins13 games
White Sox2
2025 seasonLast meeting Sep 14, 2025

Betting comparison

2025

Guardians

13 bets
7-6-0Wins ยท Losses ยท Pushes
Win rate
53.85%
ROI
+17.07%
Units
+2.22u

White Sox

13 bets
6-7-0Wins ยท Losses ยท Pushes
Win rate
46.15%
ROI
-22.97%
Units
-2.99u

Closing lines ยท Flat 1u per bet ยท Methodology

Scoring per game

Average runs
Guardians4.3
White Sox2.5
Combined6.8

Recent meetings

Bet results from the Guardians perspective. Spread values show the favoriteโ€™s closing line.

White SoxAway2
GuardiansHome3
Run lineMissFav -1.5
MoneylineWin
TotalUnder8
White SoxAway1
GuardiansHome3
Run lineCoverFav -1.5
MoneylineWin
TotalUnder7.5
White SoxAway0
GuardiansHome4
Run lineCoverFav -1.5
MoneylineWin
TotalUnder7.5
GuardiansAway4
White SoxHome6
Run lineMissFav -1.5
MoneylineLoss
TotalOver9
GuardiansAway3
White SoxHome1
Run lineCoverFav -1.5
MoneylineWin
TotalUnder8.5

About this matchup

What is the Cleveland Guardians vs Chicago White Sox 2025 record?

The Cleveland Guardians are 11-2 against the Chicago White Sox in 2025 in head-to-head matchups.

What is the Cleveland Guardians ATS record vs the Chicago White Sox?

The Cleveland Guardians are 7-6-0 against the spread vs the Chicago White Sox in 2025 on DraftKings, with +17.07% ROI.

Do Cleveland Guardians vs Chicago White Sox games go over or under?

Cleveland Guardians vs Chicago White Sox games average 6.8 total runs in 2025. The Over has hit 30.77% of the time.

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