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MLB ยท Head to head

White Sox vs Guardians

White Sox2
Series wins13 games
Guardians11
2025 seasonLast meeting Sep 14, 2025

Betting comparison

2025

White Sox

13 bets
6-7-0Wins ยท Losses ยท Pushes
Win rate
46.15%
ROI
-22.97%
Units
-2.99u

Guardians

13 bets
7-6-0Wins ยท Losses ยท Pushes
Win rate
53.85%
ROI
+17.07%
Units
+2.22u

Closing lines ยท Flat 1u per bet ยท Methodology

Scoring per game

Average runs
White Sox2.5
Guardians4.3
Combined6.8

Recent meetings

Bet results from the White Sox perspective. Spread values show the favoriteโ€™s closing line.

White SoxAway2
GuardiansHome3
Run lineCoverFav -1.5
MoneylineLoss
TotalUnder8
White SoxAway1
GuardiansHome3
Run lineMissFav -1.5
MoneylineLoss
TotalUnder7.5
White SoxAway0
GuardiansHome4
Run lineMissFav -1.5
MoneylineLoss
TotalUnder7.5
GuardiansAway4
White SoxHome6
Run lineCoverFav -1.5
MoneylineWin
TotalOver9
GuardiansAway3
White SoxHome1
Run lineMissFav -1.5
MoneylineLoss
TotalUnder8.5

About this matchup

What is the Chicago White Sox vs Cleveland Guardians 2025 record?

The Chicago White Sox are 2-11 against the Cleveland Guardians in 2025 in head-to-head matchups.

What is the Chicago White Sox ATS record vs the Cleveland Guardians?

The Chicago White Sox are 6-7-0 against the spread vs the Cleveland Guardians in 2025 on DraftKings, with -22.97% ROI.

Do Chicago White Sox vs Cleveland Guardians games go over or under?

Chicago White Sox vs Cleveland Guardians games average 6.8 total runs in 2025. The Over has hit 30.77% of the time.

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