White Sox vs Guardians Betting Record — 2025
Against the Spread
6-7-0
Win %
46.15%
ROI
-22.97%
Units
-3.0
Moneyline
2-11-0
Win %
15.38%
ROI
-68%
Units
-8.8
Over Rate
4-9-0
Win %
30.77%
ROI
-41.59%
Units
-5.4
From the Other Side — Guardians vs White Sox
Against the Spread
7-6-0
Win %
53.85%
ROI
+17.07%
Units
+2.2
Moneyline
11-2-0
Win %
84.62%
ROI
+39.08%
Units
+5.1
Over Rate
4-9-0
Win %
30.77%
ROI
-41.59%
Units
-5.4
Venue Splits
White Sox Home
3-4-0 ATS
42.86% • -29%
2-5-0 ML (28.57%)
Guardians Home
3-3-0 ATS
50% • +7.66%
6-0-0 ML (100%)
Scoring Averages
White Sox
2.5
PPG
4.3
allowed
Total
6.8
Avg
13
games
Guardians
4.3
PPG
2.5
allowed
Recent Matchups (2025)
| Date | Score | ATS | ML | O/U |
|---|---|---|---|---|
| 09/142025-09-14 | L 3-2 | ✓ | L | U |
| 09/132025-09-13 | L 3-1 | ✗ | L | U |
| 09/122025-09-12 | L 4-0 | ✗ | L | U |
| 08/102025-08-10 | W 6-4 | ✓ | W | O |
| 08/092025-08-09 | L 1-3 | ✗ | L | U |
| 08/082025-08-08 | L 5-9 | ✗ | L | O |
| 07/132025-07-13 | L 5-6 | ✓ | L | O |
| 07/122025-07-12 | L 2-6 | ✗ | L | U |
| 07/112025-07-11 | W 5-4 | ✓ | W | O |
| 07/112025-07-11 | L 2-4 | ✗ | L | U |
| 04/102025-04-10 | L 6-1 | ✗ | L | U |
| 04/092025-04-09 | L 3-2 | ✓ | L | U |
| 04/082025-04-08 | L 1-0 | ✓ | L | U |
Frequently Asked Questions
What is the Chicago White Sox vs Cleveland Guardians all-time record?
The Chicago White Sox are 2-11 against the Cleveland Guardians in 2025 in head-to-head matchups.
What is the Chicago White Sox ATS record vs the Cleveland Guardians?
The Chicago White Sox are 6-7-0 against the spread vs the Cleveland Guardians in 2025 on DraftKings, with -22.97% ROI.
Do Chicago White Sox vs Cleveland Guardians games go over or under?
Chicago White Sox vs Cleveland Guardians games average 6.8 total points in 2025. The Over has hit 30.77% of the time.

Inside Edge
