The San Francisco 49ers are 12-7-0 Against the Spread in 2025-26
NFLNFC • NFC West
The San Francisco 49ers are 12-7-0 ats record in 2025-26, a 63.16% rate with +21.48% ROI on flat $100 bets at closing odds. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official NFL box scores.
Against the Spread
12-7-0
Win %
63.16%
ROI
+21.48%
Games
19
49ers Monthly Performance
+21.6%12-7 · +4.1u
-5%
-0.5%
+54.2%
+89.3%
-36.4%
Sep
2-2
2-2
Oct
2-2
2-2
Nov
4-1
4-1
Dec
3-0
3-0
Jan
1-2
1-2
Home / Away ATS
Home
4-4-0
50%-4.02%
Away
8-3-0
72.73%+40.03%
Favorite / Underdog ATS
As Favorite
10-2-0
83.33%+59.93%
As Underdog
2-5-0
28.57%-44.44%
Recent Games (2025-26)
| Date | Opponent | Score | ATS |
|---|---|---|---|
| 2026-01-17 |  @ Seahawks | L 41-6 | ✗ |
| 2026-01-11 |  @ Eagles | W 19-23 | ✓ |
| 2026-01-03 | vs Seahawks | L 3-13 | ✗ |
| 2025-12-28 |  vs Bears | W 42-38 | ✓ |
| 2025-12-22 |  @ Colts | W 27-48 | ✓ |
| 2025-12-14 |  vs Titans | W 37-24 | ✓ |
| 2025-11-30 |  @ Browns | W 8-26 | ✓ |
| 2025-11-24 |  vs Panthers | W 20-9 | ✓ |
| 2025-11-16 |  @ Cardinals | W 22-41 | ✓ |
| 2025-11-09 |  vs Rams | L 26-42 | ✗ |
Frequently Asked Questions
What is the San Francisco 49ers ats record in 2025-26?
The San Francisco 49ers are 12-7-0 (63.16%) ats record in 2025-26 on DraftKings, with +21.48% ROI.
What is the San Francisco 49ers home vs away ats record?
Home: 4-4-0 (-4.02% ROI). Away: 8-3-0 (+40.03% ROI).
More 49ers Stats (2025-26)
Compare ATS Record
Against the Spread Record for the San Francisco 49ers in the 2025-26 season on LineTerminal. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results. LineTerminal offers advanced system-building tools to research San Francisco 49ers betting trends across 80+ filters and 5+ years of data.
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