Penn State Nittany Lions Lead Michigan State Spartans 3-0 in Head-to-Head Matchups

NCAAF0-2-1 ATS (0%)Updated November 15, 2025

The Michigan State Spartans are 0-3 against the Penn State Nittany Lions in head-to-head matchups, going 0-2-1 ATS (0% cover rate) with -100% ROI. Games average 43.7 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official NCAAF box scores.

See methodology.

Spartans vs Nittany Lions Betting Record

Against the Spread

0-2-1

Win %

ROI

-100%

Units

-2.0

Moneyline

0-3-0

Win %

ROI

-100%

Units

-3.0

Over Rate

0-3-0

Win %

ROI

-100%

Units

-3.0

From the Other Side — Nittany Lions vs Spartans

Against the Spread

2-0-1

Win %

100%

ROI

+90.94%

Units

+1.8

Moneyline

3-0-0

Win %

100%

ROI

+16.51%

Units

+0.5

Over Rate

0-3-0

Win %

ROI

-100%

Units

-3.0

Venue Splits

Spartans Home

0-2-0 ATS

0% • -100%

0-2-0 ML (0%)

Nittany Lions Home

1-0-0 ML (100%)

Scoring Averages

Spartans

8.7

PPG

allowed

Total

43.7

Avg

games

Nittany Lions

PPG

8.7

allowed

Recent Matchups

Date	Matchup	Score	Spread	ATS	ML	O/U
11/152025-11-15	Nittany Lions @ Spartans	L 10-28	-7	✗	L	U
11/242023-11-24	Nittany Lions @ Spartans	L 0-42	-22.5	✗	L	U
11/262022-11-26	Spartans @ Nittany Lions	L 35-16	-19	P	L	U

Frequently Asked Questions

What is the Michigan State Spartans vs Penn State Nittany Lions all-time record?

The Michigan State Spartans are 0-3 against the Penn State Nittany Lions in head-to-head matchups.

What is the Michigan State Spartans ATS record vs the Penn State Nittany Lions?

The Michigan State Spartans are 0-2-1 against the spread vs the Penn State Nittany Lions on DraftKings, with -100% ROI.

Do Michigan State Spartans vs Penn State Nittany Lions games go over or under?

Michigan State Spartans vs Penn State Nittany Lions games average 43.7 total points. The Over has hit 0% of the time.

More Spartans Matchups

See from Nittany Lions perspective

Head-to-head betting record for Michigan State Spartans vs Penn State Nittany Lions on LineTerminal. The Spartans are 0-3 straight up against the Nittany Lions and 0-2-1 against the spread (0% cover rate, -100% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.