Penn State Nittany Lions Lead Michigan State Spartans 3-0 in Head-to-Head Matchups

NCAAF2-0-1 ATS (100%)Updated November 15, 2025

The Penn State Nittany Lions are 3-0 against the Michigan State Spartans in head-to-head matchups, going 2-0-1 ATS (100% cover rate) with +90.94% ROI. Games average 43.7 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official NCAAF box scores.

See methodology.

Nittany Lions vs Spartans Betting Record

Against the Spread

2-0-1

Win %

100%

ROI

+90.94%

Units

+1.8

Moneyline

3-0-0

Win %

100%

ROI

+16.51%

Units

+0.5

Over Rate

0-3-0

Win %

ROI

-100%

Units

-3.0

From the Other Side — Spartans vs Nittany Lions

Against the Spread

0-2-1

Win %

ROI

-100%

Units

-2.0

Moneyline

0-3-0

Win %

ROI

-100%

Units

-3.0

Over Rate

0-3-0

Win %

ROI

-100%

Units

-3.0

Venue Splits

Nittany Lions Home

1-0-0 ML (100%)

Spartans Home

0-2-0 ATS

0% • -100%

0-2-0 ML (0%)

Scoring Averages

Nittany Lions

PPG

8.7

allowed

Total

43.7

Avg

games

Spartans

8.7

PPG

allowed

Recent Matchups

Date	Matchup	Score	Spread	ATS	ML	O/U
11/152025-11-15	Nittany Lions @ Spartans	W 10-28	-7	✓	W	U
11/242023-11-24	Nittany Lions @ Spartans	W 0-42	-22.5	✓	W	U
11/262022-11-26	Spartans @ Nittany Lions	W 35-16	-19	P	W	U

Frequently Asked Questions

What is the Penn State Nittany Lions vs Michigan State Spartans all-time record?

The Penn State Nittany Lions are 3-0 against the Michigan State Spartans in head-to-head matchups.

What is the Penn State Nittany Lions ATS record vs the Michigan State Spartans?

The Penn State Nittany Lions are 2-0-1 against the spread vs the Michigan State Spartans on DraftKings, with +90.94% ROI.

Do Penn State Nittany Lions vs Michigan State Spartans games go over or under?

Penn State Nittany Lions vs Michigan State Spartans games average 43.7 total points. The Over has hit 0% of the time.

More Nittany Lions Matchups

See from Spartans perspective

Head-to-head betting record for Penn State Nittany Lions vs Michigan State Spartans on LineTerminal. The Nittany Lions are 3-0 straight up against the Spartans and 2-0-1 against the spread (100% cover rate, +90.94% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.