Iowa Hawkeyes Lead Michigan State Spartans 2-1 in Head-to-Head Matchups

NCAAF2-0-1 ATS (100%)Updated November 22, 2025

The Michigan State Spartans are 1-2 against the Iowa Hawkeyes in head-to-head matchups, going 2-0-1 ATS (100% cover rate) with +93.66% ROI. Games average 43.7 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official NCAAF box scores.

See methodology.

Michigan State Spartans vs Iowa Hawkeyes Betting Record

Against the Spread

2-0-1

Win %

100%

ROI

+93.66%

Units

+1.9

Moneyline

1-2-0

Win %

33.33%

ROI

+8.33%

Units

+0.3

Over Rate

2-1-0

Win %

66.67%

ROI

+26.73%

Units

+0.8

From the Other Side — Iowa Hawkeyes vs Michigan State Spartans

Against the Spread

0-2-1

Win %

ROI

-100%

Units

-2.0

Moneyline

2-1-0

Win %

66.67%

ROI

-20.52%

Units

-0.6

Over Rate

2-1-0

Win %

66.67%

ROI

+26.73%

Units

+0.8

Venue Splits

Michigan State Spartans Home

1-0-0 ATS

100% • +89.29%

1-0-0 ML (100%)

Iowa Hawkeyes Home

0-1-1 ATS

0% • -100%

2-0-0 ML (100%)

Scoring Averages

Michigan State Spartans

21.7

PPG

allowed

Total

43.7

Avg

games

Iowa Hawkeyes

PPG

21.7

allowed

Recent Matchups

Date	Matchup	Score	Spread	ATS	ML	O/U
11/222025-11-22	Michigan State Spartans @ Iowa Hawkeyes	L 20-17	-16.5	✓	L	U
10/192024-10-19	Iowa Hawkeyes @ Michigan State Spartans	W 32-20	-7	✓	W	O
09/302023-09-30	Michigan State Spartans @ Iowa Hawkeyes	L 26-16	-10	P	L	O

Frequently Asked Questions

What is the Michigan State Spartans vs Iowa Hawkeyes all-time record?

The Michigan State Spartans are 1-2 against the Iowa Hawkeyes in head-to-head matchups.

What is the Michigan State Spartans ATS record vs the Iowa Hawkeyes?

The Michigan State Spartans are 2-0-1 against the spread vs the Iowa Hawkeyes on DraftKings, with +93.66% ROI.

Do Michigan State Spartans vs Iowa Hawkeyes games go over or under?

Michigan State Spartans vs Iowa Hawkeyes games average 43.7 total points. The Over has hit 66.67% of the time.

More Michigan State Spartans Matchups

vs Illinois Fighting Illini

vs Indiana Hoosiers

vs Maryland Terrapins

vs Michigan Wolverines

vs Minnesota Golden Gophers

vs Nebraska Cornhuskers

See from Iowa Hawkeyes perspective

Head-to-head betting record for Michigan State Spartans vs Iowa Hawkeyes on LineTerminal. The Michigan State Spartans are 1-2 straight up against the Iowa Hawkeyes and 2-0-1 against the spread (100% cover rate, +93.66% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.