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Louisville Cardinals Lead Pittsburgh Panthers 1-0 in Head-to-Head Matchups (2025-26)

NCAAF1-0-0 ATS (100%)

The Louisville Cardinals are 1-0 against the Pittsburgh Panthers in 2025-26 in head-to-head matchups, going 1-0-0 ATS (100% cover rate) with +92.59% ROI. Games average 61 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official NCAAF box scores.

See methodology.

Louisville Cardinals vs Pittsburgh Panthers Betting Record — 2025-26

Against the Spread
1-0-0
Win %
100%
ROI
+92.59%
Units
+0.9
Moneyline
1-0-0
Win %
100%
ROI
+64.52%
Units
+0.7
Over Rate
1-0-0
Win %
100%
ROI
+86.96%
Units
+0.9

From the Other Side — Pittsburgh Panthers vs Louisville Cardinals

Against the Spread
0-1-0
Win %
0%
ROI
-100%
Units
-1.0
Moneyline
0-1-0
Win %
0%
ROI
-100%
Units
-1.0
Over Rate
1-0-0
Win %
100%
ROI
+86.96%
Units
+0.9

Venue Splits

Louisville Cardinals Home
Pittsburgh Panthers Home
0-1-0 ATS
0% • -100%
0-1-0 ML (0%)

Scoring Averages

Louisville Cardinals
34
PPG
27
allowed
Total
61
Avg
1
games
Pittsburgh Panthers
27
PPG
34
allowed

Recent Matchups (2025-26)

DateScoreATSMLO/U
09/27W 27-34WO

Frequently Asked Questions

What is the Louisville Cardinals vs Pittsburgh Panthers 2025-26 record?
The Louisville Cardinals are 1-0 against the Pittsburgh Panthers in 2025-26 in head-to-head matchups.
What is the Louisville Cardinals ATS record vs the Pittsburgh Panthers?
The Louisville Cardinals are 1-0-0 against the spread vs the Pittsburgh Panthers in 2025-26 on DraftKings, with +92.59% ROI.
Do Louisville Cardinals vs Pittsburgh Panthers games go over or under?
Louisville Cardinals vs Pittsburgh Panthers games average 61 total points in 2025-26. The Over has hit 100% of the time.

More Louisville Cardinals Matchups

Head-to-head betting record for Louisville Cardinals vs Pittsburgh Panthers in the 2025-26 season on LineTerminal. The Louisville Cardinals are 1-0 straight up against the Pittsburgh Panthers and 1-0-0 against the spread (100% cover rate, +92.59% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

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