Clemson TigersAway20
Louisville CardinalsHome19SpreadMissFav -1.5
MoneylineLoss
TotalUnder50.5
NCAAF · Head to head
Louisville Cardinals vs Clemson Tigers
2025-26 seasonLast meeting Nov 14, 2025
Betting comparison
2025-26
Louisville Cardinals
1 bets0-1-0Wins · Losses · Pushes
- Win rate
- 0%
- ROI
- -100%
- Units
- -1u
Clemson Tigers
1 bets1-0-0Wins · Losses · Pushes
- Win rate
- 100%
- ROI
- +95.24%
- Units
- +0.95u
Closing lines · Flat 1u per bet · Methodology
Scoring per game
Average pointsLouisville Cardinals19
Clemson Tigers20
Combined39
Recent meetings
Bet results from the Louisville Cardinals perspective. Spread values show the favorite’s closing line.
Clemson TigersAway20Louisville CardinalsHome19More Louisville Cardinals matchups
About this matchup
What is the Louisville Cardinals vs Clemson Tigers 2025-26 record?
The Louisville Cardinals are 0-1 against the Clemson Tigers in 2025-26 in head-to-head matchups.
What is the Louisville Cardinals ATS record vs the Clemson Tigers?
The Louisville Cardinals are 0-1-0 against the spread vs the Clemson Tigers in 2025-26 on DraftKings, with -100% ROI.
Do Louisville Cardinals vs Clemson Tigers games go over or under?
Louisville Cardinals vs Clemson Tigers games average 39 total points in 2025-26. The Over has hit 0% of the time.