Louisville CardinalsAway34
Pittsburgh PanthersHome27SpreadMissFav -3
MoneylineLoss
TotalOver53.5
NCAAF · Head to head
Pittsburgh Panthers vs Louisville Cardinals
2025-26 seasonLast meeting Sep 27, 2025
Betting comparison
2025-26
Pittsburgh Panthers
1 bets0-1-0Wins · Losses · Pushes
- Win rate
- 0%
- ROI
- -100%
- Units
- -1u
Louisville Cardinals
1 bets1-0-0Wins · Losses · Pushes
- Win rate
- 100%
- ROI
- +92.59%
- Units
- +0.93u
Closing lines · Flat 1u per bet · Methodology
Scoring per game
Average pointsPittsburgh Panthers27
Louisville Cardinals34
Combined61
Recent meetings
Bet results from the Pittsburgh Panthers perspective. Spread values show the favorite’s closing line.
Louisville CardinalsAway34Pittsburgh PanthersHome27More Pittsburgh Panthers matchups
About this matchup
What is the Pittsburgh Panthers vs Louisville Cardinals 2025-26 record?
The Pittsburgh Panthers are 0-1 against the Louisville Cardinals in 2025-26 in head-to-head matchups.
What is the Pittsburgh Panthers ATS record vs the Louisville Cardinals?
The Pittsburgh Panthers are 0-1-0 against the spread vs the Louisville Cardinals in 2025-26 on DraftKings, with -100% ROI.
Do Pittsburgh Panthers vs Louisville Cardinals games go over or under?
Pittsburgh Panthers vs Louisville Cardinals games average 61 total points in 2025-26. The Over has hit 100% of the time.