Duke Blue Devils Lead Clemson Tigers 2-0 in Head-to-Head Matchups

NCAAF0-2-0 ATS (0%)Updated November 1, 2025

The Clemson Tigers are 0-2 against the Duke Blue Devils in head-to-head matchups, going 0-2-0 ATS (0% cover rate) with -100% ROI. Games average 63 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official NCAAF box scores.

See methodology.

Tigers vs Blue Devils Betting Record

Against the Spread

0-2-0

Win %

ROI

-100%

Units

-2.0

Moneyline

0-2-0

Win %

ROI

-100%

Units

-2.0

Over Rate

1-1-0

Win %

50%

ROI

-6.52%

Units

-0.1

From the Other Side — Blue Devils vs Tigers

Against the Spread

2-0-0

Win %

100%

ROI

+90.1%

Units

+1.8

Moneyline

2-0-0

Win %

100%

ROI

+250%

Units

+5.0

Over Rate

1-1-0

Win %

50%

ROI

-6.52%

Units

-0.1

Venue Splits

Tigers Home

0-1-0 ATS

0% • -100%

0-1-0 ML (0%)

Blue Devils Home

1-0-0 ATS

100% • +90.91%

1-0-0 ML (100%)

Scoring Averages

Tigers

PPG

allowed

Total

Avg

games

Blue Devils

PPG

allowed

Recent Matchups

Date	Matchup	Score	Spread	ATS	ML	O/U
11/012025-11-01	Blue Devils @ Tigers	L 45-46	-4	✗	L	O
09/042023-09-04	Tigers @ Blue Devils	L 28-7	-12	✗	L	U

Frequently Asked Questions

What is the Clemson Tigers vs Duke Blue Devils all-time record?

The Clemson Tigers are 0-2 against the Duke Blue Devils in head-to-head matchups.

What is the Clemson Tigers ATS record vs the Duke Blue Devils?

The Clemson Tigers are 0-2-0 against the spread vs the Duke Blue Devils on DraftKings, with -100% ROI.

Do Clemson Tigers vs Duke Blue Devils games go over or under?

Clemson Tigers vs Duke Blue Devils games average 63 total points. The Over has hit 50% of the time.

More Tigers Matchups

See from Blue Devils perspective

Head-to-head betting record for Clemson Tigers vs Duke Blue Devils on LineTerminal. The Tigers are 0-2 straight up against the Blue Devils and 0-2-0 against the spread (0% cover rate, -100% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.