Duke Blue Devils Lead Clemson Tigers 2-0 in Head-to-Head Matchups

NCAAF2-0-0 ATS (100%)Updated November 1, 2025

The Duke Blue Devils are 2-0 against the Clemson Tigers in head-to-head matchups, going 2-0-0 ATS (100% cover rate) with +90.1% ROI. Games average 63 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official NCAAF box scores.

See methodology.

Blue Devils vs Tigers Betting Record

Against the Spread

2-0-0

Win %

100%

ROI

+90.1%

Units

+1.8

Moneyline

2-0-0

Win %

100%

ROI

+250%

Units

+5.0

Over Rate

1-1-0

Win %

50%

ROI

-6.52%

Units

-0.1

From the Other Side — Tigers vs Blue Devils

Against the Spread

0-2-0

Win %

ROI

-100%

Units

-2.0

Moneyline

0-2-0

Win %

ROI

-100%

Units

-2.0

Over Rate

1-1-0

Win %

50%

ROI

-6.52%

Units

-0.1

Venue Splits

Blue Devils Home

1-0-0 ATS

100% • +90.91%

1-0-0 ML (100%)

Tigers Home

0-1-0 ATS

0% • -100%

0-1-0 ML (0%)

Scoring Averages

Blue Devils

PPG

allowed

Total

Avg

games

Tigers

PPG

allowed

Recent Matchups

Date	Matchup	Score	Spread	ATS	ML	O/U
11/012025-11-01	Blue Devils @ Tigers	W 45-46	-4	✓	W	O
09/042023-09-04	Tigers @ Blue Devils	W 28-7	-12	✓	W	U

Frequently Asked Questions

What is the Duke Blue Devils vs Clemson Tigers all-time record?

The Duke Blue Devils are 2-0 against the Clemson Tigers in head-to-head matchups.

What is the Duke Blue Devils ATS record vs the Clemson Tigers?

The Duke Blue Devils are 2-0-0 against the spread vs the Clemson Tigers on DraftKings, with +90.1% ROI.

Do Duke Blue Devils vs Clemson Tigers games go over or under?

Duke Blue Devils vs Clemson Tigers games average 63 total points. The Over has hit 50% of the time.

More Blue Devils Matchups

See from Tigers perspective

Head-to-head betting record for Duke Blue Devils vs Clemson Tigers on LineTerminal. The Blue Devils are 2-0 straight up against the Tigers and 2-0-0 against the spread (100% cover rate, +90.1% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.