Louisville CardinalsAway6
SMU MustangsHome38SpreadCoverFav -4
MoneylineWin
TotalUnder49.5
NCAAF · Head to head
SMU Mustangs vs Louisville Cardinals
2025-26 seasonLast meeting Nov 22, 2025
Betting comparison
2025-26
SMU Mustangs
1 bets1-0-0Wins · Losses · Pushes
- Win rate
- 100%
- ROI
- +92.59%
- Units
- +0.93u
Louisville Cardinals
1 bets0-1-0Wins · Losses · Pushes
- Win rate
- 0%
- ROI
- -100%
- Units
- -1u
Closing lines · Flat 1u per bet · Methodology
Scoring per game
Average pointsSMU Mustangs38
Louisville Cardinals6
Combined44
Recent meetings
Bet results from the SMU Mustangs perspective. Spread values show the favorite’s closing line.
Louisville CardinalsAway6SMU MustangsHome38More SMU Mustangs matchups
About this matchup
What is the SMU Mustangs vs Louisville Cardinals 2025-26 record?
The SMU Mustangs are 1-0 against the Louisville Cardinals in 2025-26 in head-to-head matchups.
What is the SMU Mustangs ATS record vs the Louisville Cardinals?
The SMU Mustangs are 1-0-0 against the spread vs the Louisville Cardinals in 2025-26 on DraftKings, with +92.59% ROI.
Do SMU Mustangs vs Louisville Cardinals games go over or under?
SMU Mustangs vs Louisville Cardinals games average 44 total points in 2025-26. The Over has hit 0% of the time.