Virginia CavaliersAway30
Louisville CardinalsHome27SpreadMissFav -6.5
MoneylineLoss
TotalUnder60.5
NCAAF · Head to head
Louisville Cardinals vs Virginia Cavaliers
All recorded seasonsLast meeting Oct 4, 2025
Betting comparison
All seasons
Louisville Cardinals
4 bets1-3-0Wins · Losses · Pushes
- Win rate
- 25%
- ROI
- -52.27%
- Units
- -2.09u
Virginia Cavaliers
4 bets3-1-0Wins · Losses · Pushes
- Win rate
- 75%
- ROI
- +43.86%
- Units
- +1.75u
Closing lines · Flat 1u per bet · Methodology
Scoring per game
Average pointsLouisville Cardinals29
Virginia Cavaliers22.8
Combined51.8
Recent meetings
Bet results from the Louisville Cardinals perspective. Spread values show the favorite’s closing line.
Virginia CavaliersAway30Louisville CardinalsHome27Louisville CardinalsAway24Virginia CavaliersHome20SpreadMissFav -7
MoneylineWin
TotalUnder54
Virginia CavaliersAway24Louisville CardinalsHome31SpreadMissFav -20
MoneylineWin
TotalOver49.5
Louisville CardinalsAway34Virginia CavaliersHome17SpreadCoverFav -1.5
MoneylineWin
TotalOver47.5
More Louisville Cardinals matchups
About this matchup
What is the Louisville Cardinals vs Virginia Cavaliers all-time record?
The Louisville Cardinals are 3-1 against the Virginia Cavaliers in head-to-head matchups.
What is the Louisville Cardinals ATS record vs the Virginia Cavaliers?
The Louisville Cardinals are 1-3-0 against the spread vs the Virginia Cavaliers on DraftKings, with -52.27% ROI.
Do Louisville Cardinals vs Virginia Cavaliers games go over or under?
Louisville Cardinals vs Virginia Cavaliers games average 51.8 total points. The Over has hit 50% of the time.