Virginia CavaliersAway30
Louisville CardinalsHome27SpreadCoverFav -6.5
MoneylineWin
TotalUnder60.5
NCAAF · Head to head
Virginia Cavaliers vs Louisville Cardinals
All recorded seasonsLast meeting Oct 4, 2025
Betting comparison
All seasons
Virginia Cavaliers
4 bets3-1-0Wins · Losses · Pushes
- Win rate
- 75%
- ROI
- +43.86%
- Units
- +1.75u
Louisville Cardinals
4 bets1-3-0Wins · Losses · Pushes
- Win rate
- 25%
- ROI
- -52.27%
- Units
- -2.09u
Closing lines · Flat 1u per bet · Methodology
Scoring per game
Average pointsVirginia Cavaliers22.8
Louisville Cardinals29
Combined51.8
Recent meetings
Bet results from the Virginia Cavaliers perspective. Spread values show the favorite’s closing line.
Virginia CavaliersAway30Louisville CardinalsHome27Louisville CardinalsAway24Virginia CavaliersHome20SpreadCoverFav -7
MoneylineLoss
TotalUnder54
Virginia CavaliersAway24Louisville CardinalsHome31SpreadCoverFav -20
MoneylineLoss
TotalOver49.5
Louisville CardinalsAway34Virginia CavaliersHome17SpreadMissFav -1.5
MoneylineLoss
TotalOver47.5
More Virginia Cavaliers matchups
About this matchup
What is the Virginia Cavaliers vs Louisville Cardinals all-time record?
The Virginia Cavaliers are 1-3 against the Louisville Cardinals in head-to-head matchups.
What is the Virginia Cavaliers ATS record vs the Louisville Cardinals?
The Virginia Cavaliers are 3-1-0 against the spread vs the Louisville Cardinals on DraftKings, with +43.86% ROI.
Do Virginia Cavaliers vs Louisville Cardinals games go over or under?
Virginia Cavaliers vs Louisville Cardinals games average 51.8 total points. The Over has hit 50% of the time.