Louisville Cardinals 2025-26 Schedule
2025-26 · 9-4 overall · 4-9 ATS · 13 games
The Louisville Cardinals are 9-4 in 2025-26 across 13 games, going 4-9 against the spread (31% cover rate). Closing lines from DraftKings, FanDuel, and BetMGM, graded against official NCAAF box scores.
| Date | Opponent | Score | ATS | ML | O/U |
|---|---|---|---|---|---|
| 2025-12-23 |  vs Rockets | W 27-22 | ✗ | W | O |
| 2025-11-29 |  vs Wildcats | W 41-0 | ✓ | W | U |
| 2025-11-22 |  @ Mustangs | L 38-6 | ✗ | L | U |
| 2025-11-14 |  vs Tigers | L 19-20 | ✗ | L | U |
| 2025-11-08 |  vs Golden Bears | L 26-29 | ✗ | L | O |
| 2025-11-01 |  @ Hokies | W 16-28 | ✓ | W | U |
| 2025-10-25 |  vs Eagles | W 38-24 | ✗ | W | O |
| 2025-10-17 |  @ Hurricanes | W 21-24 | ✓ | W | U |
| 2025-10-04 |  vs Cavaliers | L 27-30 | ✗ | L | U |
| 2025-09-27 |  @ Panthers | W 27-34 | ✓ | W | O |
| 2025-09-20 |  vs Falcons | W 40-17 | ✗ | W | O |
| 2025-09-05 |  vs Dukes | W 28-14 | ✗ | W | U |
| 2025-08-30 |  vs Colonels | W 51-17 | ✗ | W | U |
Inside Edge