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Home/NCAAF Schedule/Cardinals @ Mustangs

Cardinals 6, Mustangs 38 — Nov 22, 2025 Recap

SMU Mustangs beat Louisville Cardinals 6-38 on Nov 22, 2025.

Played November 22, 2025

Game FAQ — score, spread, and total

Who won Louisville Cardinals vs SMU Mustangs on Nov 22, 2025?

SMU Mustangs won 6-38 on Nov 22, 2025.

See methodology for grading rules and ROI calculation.

NCAAF Schedule/Cardinals @ Mustangs

NCAAFSAT, NOV 22, 202511:00 AM CDT

Away

CardinalsLouisville Cardinals6

Final

Home

MustangsSMU Mustangs38

Betting Results

Spread

Mustangs covered

Mustangs -3.5

Total

Under

44 / 49.5

Moneyline

Mustangs

-185

Loading probability

Pre-Game Notes1 note

SMU

Rest advantage

+6 days off

ScoringSeason · per game

Team

PPG

Scored

OPP

Allowed

MARGIN

Per game

Cardinals

31.5★

21.5★

+10.0★

Mustangs

32.2★

20.4★

+11.8★

Edge

Mustangs +0.7

Mustangs +1.1

Mustangs +1.8

Last 10 · Trend

Cardinals

31.5avg

Mustangs

32.2avg

Recent FormLast 10

Straight-Up

Cardinals

7-370%

W

W

W

W

L

W

W

W

L

L

Mustangs

7-370%

W

L

W

L

W

W

W

L

W

W

Against the Spread

Cardinals

3-730%

L

L

L

W

L

W

L

W

L

L

Mustangs

4-640%

L

L

L

L

L

W

W

L

W

W

Season Records2025-26 · 10g / 10g

Team

SU

ATS

O/U

Cardinals

Overall

70%7-3

30%3-7

40%4-6

Mustangs

Overall

70%7-3

40%4-6

30%3-7

Matchup VenueRoad / Home splits

Team

SU

ATS

O/U

Cardinals

On Road

100%3-0

100%3-0

33%1-2

Mustangs

At Home

80%4-1

40%2-3

20%1-4

EV Picks