Kansas Jayhawks Lead Iowa State Cyclones 3-1 in Head-to-Head Matchups

NCAAF3-1-0 ATS (75%)Updated November 22, 2025

The Kansas Jayhawks are 3-1 against the Iowa State Cyclones in head-to-head matchups, going 3-1-0 ATS (75% cover rate) with +44.26% ROI. Games average 51.8 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official NCAAF box scores.

See methodology.

Jayhawks vs Cyclones Betting Record

Against the Spread

3-1-0

Win %

75%

ROI

+44.26%

Units

+1.8

Moneyline

3-1-0

Win %

75%

ROI

+64.75%

Units

+2.6

Over Rate

1-3-0

Win %

25%

ROI

-52.27%

Units

-2.1

From the Other Side — Cyclones vs Jayhawks

Against the Spread

1-3-0

Win %

25%

ROI

-53.81%

Units

-2.1

Moneyline

1-3-0

Win %

25%

ROI

-59.57%

Units

-2.4

Over Rate

1-3-0

Win %

25%

ROI

-52.27%

Units

-2.1

Venue Splits

Jayhawks Home

2-0-0 ATS

100% • +93.07%

2-0-0 ML (100%)

Cyclones Home

1-1-0 ATS

50% • -7.63%

1-1-0 ML (50%)

Scoring Averages

Jayhawks

25.3

PPG

26.5

allowed

Total

51.8

Avg

games

Cyclones

26.5

PPG

25.3

allowed

Recent Matchups

Date	Matchup	Score	Spread	ATS	ML	O/U
11/222025-11-22	Jayhawks @ Cyclones	L 38-14	-3	✗	L	U
11/092024-11-09	Cyclones @ Jayhawks	W 45-36	-1.5	✓	W	O
11/042023-11-04	Jayhawks @ Cyclones	W 21-28	-2.5	✓	W	U
10/012022-10-01	Cyclones @ Jayhawks	W 14-11	-3	✓	W	U

Frequently Asked Questions

What is the Kansas Jayhawks vs Iowa State Cyclones all-time record?

The Kansas Jayhawks are 3-1 against the Iowa State Cyclones in head-to-head matchups.

What is the Kansas Jayhawks ATS record vs the Iowa State Cyclones?

The Kansas Jayhawks are 3-1-0 against the spread vs the Iowa State Cyclones on DraftKings, with +44.26% ROI.

Do Kansas Jayhawks vs Iowa State Cyclones games go over or under?

Kansas Jayhawks vs Iowa State Cyclones games average 51.8 total points. The Over has hit 25% of the time.

More Jayhawks Matchups

See from Cyclones perspective

Head-to-head betting record for Kansas Jayhawks vs Iowa State Cyclones on LineTerminal. The Jayhawks are 3-1 straight up against the Cyclones and 3-1-0 against the spread (75% cover rate, +44.26% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.