Kansas Jayhawks Lead Iowa State Cyclones 3-1 in Head-to-Head Matchups

NCAAF1-3-0 ATS (25%)Updated November 22, 2025

The Iowa State Cyclones are 1-3 against the Kansas Jayhawks in head-to-head matchups, going 1-3-0 ATS (25% cover rate) with -53.81% ROI. Games average 51.8 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official NCAAF box scores.

See methodology.

Cyclones vs Jayhawks Betting Record

Against the Spread

1-3-0

Win %

25%

ROI

-53.81%

Units

-2.1

Moneyline

1-3-0

Win %

25%

ROI

-59.57%

Units

-2.4

Over Rate

1-3-0

Win %

25%

ROI

-52.27%

Units

-2.1

From the Other Side — Jayhawks vs Cyclones

Against the Spread

3-1-0

Win %

75%

ROI

+44.26%

Units

+1.8

Moneyline

3-1-0

Win %

75%

ROI

+64.75%

Units

+2.6

Over Rate

1-3-0

Win %

25%

ROI

-52.27%

Units

-2.1

Venue Splits

Cyclones Home

1-1-0 ATS

50% • -7.63%

1-1-0 ML (50%)

Jayhawks Home

2-0-0 ATS

100% • +93.07%

2-0-0 ML (100%)

Scoring Averages

Cyclones

26.5

PPG

25.3

allowed

Total

51.8

Avg

games

Jayhawks

25.3

PPG

26.5

allowed

Recent Matchups

Date	Matchup	Score	Spread	ATS	ML	O/U
11/222025-11-22	Jayhawks @ Cyclones	W 38-14	-3	✓	W	U
11/092024-11-09	Cyclones @ Jayhawks	L 45-36	-1.5	✗	L	O
11/042023-11-04	Jayhawks @ Cyclones	L 21-28	-2.5	✗	L	U
10/012022-10-01	Cyclones @ Jayhawks	L 14-11	-3	✗	L	U

Frequently Asked Questions

What is the Iowa State Cyclones vs Kansas Jayhawks all-time record?

The Iowa State Cyclones are 1-3 against the Kansas Jayhawks in head-to-head matchups.

What is the Iowa State Cyclones ATS record vs the Kansas Jayhawks?

The Iowa State Cyclones are 1-3-0 against the spread vs the Kansas Jayhawks on DraftKings, with -53.81% ROI.

Do Iowa State Cyclones vs Kansas Jayhawks games go over or under?

Iowa State Cyclones vs Kansas Jayhawks games average 51.8 total points. The Over has hit 25% of the time.

More Cyclones Matchups

See from Jayhawks perspective

Head-to-head betting record for Iowa State Cyclones vs Kansas Jayhawks on LineTerminal. The Cyclones are 1-3 straight up against the Jayhawks and 1-3-0 against the spread (25% cover rate, -53.81% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.