Colorado Buffaloes Lead Iowa State Cyclones 1-0 in Head-to-Head Matchups

NCAAF1-0-0 ATS (100%)Updated October 11, 2025

The Colorado Buffaloes are 1-0 against the Iowa State Cyclones in head-to-head matchups, going 1-0-0 ATS (100% cover rate) with +90.91% ROI. Games average 41 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official NCAAF box scores.

See methodology.

Buffaloes vs Cyclones Betting Record

Against the Spread

1-0-0

Win %

100%

ROI

+90.91%

Units

+0.9

Moneyline

1-0-0

Win %

100%

ROI

+124%

Units

+1.2

Over Rate

0-1-0

Win %

ROI

-100%

Units

-1.0

From the Other Side — Cyclones vs Buffaloes

Against the Spread

0-1-0

Win %

ROI

-100%

Units

-1.0

Moneyline

0-1-0

Win %

ROI

-100%

Units

-1.0

Over Rate

0-1-0

Win %

ROI

-100%

Units

-1.0

Venue Splits

Buffaloes Home

1-0-0 ATS

100% • +90.91%

1-0-0 ML (100%)

Cyclones Home

Scoring Averages

Buffaloes

PPG

allowed

Total

Avg

games

Cyclones

PPG

allowed

Recent Matchups

Date	Matchup	Score	Spread	ATS	ML	O/U
10/112025-10-11	Cyclones @ Buffaloes	W 24-17	-3	✓	W	U

Frequently Asked Questions

What is the Colorado Buffaloes vs Iowa State Cyclones all-time record?

The Colorado Buffaloes are 1-0 against the Iowa State Cyclones in head-to-head matchups.

What is the Colorado Buffaloes ATS record vs the Iowa State Cyclones?

The Colorado Buffaloes are 1-0-0 against the spread vs the Iowa State Cyclones on DraftKings, with +90.91% ROI.

Do Colorado Buffaloes vs Iowa State Cyclones games go over or under?

Colorado Buffaloes vs Iowa State Cyclones games average 41 total points. The Over has hit 0% of the time.

More Buffaloes Matchups

See from Cyclones perspective

Head-to-head betting record for Colorado Buffaloes vs Iowa State Cyclones on LineTerminal. The Buffaloes are 1-0 straight up against the Cyclones and 1-0-0 against the spread (100% cover rate, +90.91% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.