Arizona Wildcats Lead Colorado Buffaloes 3-1 in Head-to-Head Matchups

NCAAF2-2-0 ATS (50%)Updated November 1, 2025

The Colorado Buffaloes are 1-3 against the Arizona Wildcats in head-to-head matchups, going 2-2-0 ATS (50% cover rate) with -4.55% ROI. Games average 59.5 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official NCAAF box scores.

See methodology.

Buffaloes vs Wildcats Betting Record

Against the Spread

2-2-0

Win %

50%

ROI

-4.55%

Units

-0.2

Moneyline

1-3-0

Win %

25%

ROI

-47.5%

Units

-1.9

Over Rate

3-1-0

Win %

75%

ROI

+43.6%

Units

+1.7

From the Other Side — Wildcats vs Buffaloes

Against the Spread

2-2-0

Win %

50%

ROI

-3.04%

Units

-0.1

Moneyline

3-1-0

Win %

75%

ROI

-1.02%

Units

-0.0

Over Rate

3-1-0

Win %

75%

ROI

+43.6%

Units

+1.7

Venue Splits

Buffaloes Home

1-1-0 ATS

50% • -4.55%

0-2-0 ML (0%)

Wildcats Home

1-1-0 ATS

50% • -2.38%

1-1-0 ML (50%)

Scoring Averages

Buffaloes

25.5

PPG

allowed

Total

59.5

Avg

games

Wildcats

PPG

25.5

allowed

Recent Matchups

Date	Matchup	Score	Spread	ATS	ML	O/U
11/012025-11-01	Wildcats @ Buffaloes	L 17-52	-4	✗	L	O
10/192024-10-19	Buffaloes @ Wildcats	W 7-34	-2.5	✓	W	U
11/112023-11-11	Wildcats @ Buffaloes	L 31-34	-8	✓	L	O
10/012022-10-01	Buffaloes @ Wildcats	L 43-20	-18	✗	L	O

Frequently Asked Questions

What is the Colorado Buffaloes vs Arizona Wildcats all-time record?

The Colorado Buffaloes are 1-3 against the Arizona Wildcats in head-to-head matchups.

What is the Colorado Buffaloes ATS record vs the Arizona Wildcats?

The Colorado Buffaloes are 2-2-0 against the spread vs the Arizona Wildcats on DraftKings, with -4.55% ROI.

Do Colorado Buffaloes vs Arizona Wildcats games go over or under?

Colorado Buffaloes vs Arizona Wildcats games average 59.5 total points. The Over has hit 75% of the time.

More Buffaloes Matchups

See from Wildcats perspective

Head-to-head betting record for Colorado Buffaloes vs Arizona Wildcats on LineTerminal. The Buffaloes are 1-3 straight up against the Wildcats and 2-2-0 against the spread (50% cover rate, -4.55% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.