Arizona Wildcats Lead Colorado Buffaloes 3-1 in Head-to-Head Matchups

NCAAF2-2-0 ATS (50%)Updated November 1, 2025

The Arizona Wildcats are 3-1 against the Colorado Buffaloes in head-to-head matchups, going 2-2-0 ATS (50% cover rate) with -3.04% ROI. Games average 59.5 total points. Closing lines from DraftKings, FanDuel, and BetMGM, graded against official NCAAF box scores.

See methodology.

Wildcats vs Buffaloes Betting Record

Against the Spread

2-2-0

Win %

50%

ROI

-3.04%

Units

-0.1

Moneyline

3-1-0

Win %

75%

ROI

-1.02%

Units

-0.0

Over Rate

3-1-0

Win %

75%

ROI

+43.6%

Units

+1.7

From the Other Side — Buffaloes vs Wildcats

Against the Spread

2-2-0

Win %

50%

ROI

-4.55%

Units

-0.2

Moneyline

1-3-0

Win %

25%

ROI

-47.5%

Units

-1.9

Over Rate

3-1-0

Win %

75%

ROI

+43.6%

Units

+1.7

Venue Splits

Wildcats Home

1-1-0 ATS

50% • -2.38%

1-1-0 ML (50%)

Buffaloes Home

1-1-0 ATS

50% • -4.55%

0-2-0 ML (0%)

Scoring Averages

Wildcats

PPG

25.5

allowed

Total

59.5

Avg

games

Buffaloes

25.5

PPG

allowed

Recent Matchups

Date	Matchup	Score	Spread	ATS	ML	O/U
11/012025-11-01	Wildcats @ Buffaloes	W 17-52	-4	✓	W	O
10/192024-10-19	Buffaloes @ Wildcats	L 7-34	-2.5	✗	L	U
11/112023-11-11	Wildcats @ Buffaloes	W 31-34	-8	✗	W	O
10/012022-10-01	Buffaloes @ Wildcats	W 43-20	-18	✓	W	O

Frequently Asked Questions

What is the Arizona Wildcats vs Colorado Buffaloes all-time record?

The Arizona Wildcats are 3-1 against the Colorado Buffaloes in head-to-head matchups.

What is the Arizona Wildcats ATS record vs the Colorado Buffaloes?

The Arizona Wildcats are 2-2-0 against the spread vs the Colorado Buffaloes on DraftKings, with -3.04% ROI.

Do Arizona Wildcats vs Colorado Buffaloes games go over or under?

Arizona Wildcats vs Colorado Buffaloes games average 59.5 total points. The Over has hit 75% of the time.

More Wildcats Matchups

See from Buffaloes perspective

Head-to-head betting record for Arizona Wildcats vs Colorado Buffaloes on LineTerminal. The Wildcats are 3-1 straight up against the Buffaloes and 2-2-0 against the spread (50% cover rate, -3.04% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.