Mustangs vs Cardinals Betting Record — 2025-26
Against the Spread
2-1-0
Win %
66.67%
ROI
+28.17%
Units
+0.8
Moneyline
1-2-0
Win %
33.33%
ROI
-13.33%
Units
-0.4
Over Rate
1-2-0
Win %
33.33%
ROI
-35.8%
Units
-1.1
From the Other Side — Cardinals vs Mustangs
Against the Spread
1-2-0
Win %
33.33%
ROI
-38.89%
Units
-1.2
Moneyline
2-1-0
Win %
66.67%
ROI
-16.61%
Units
-0.5
Over Rate
1-2-0
Win %
33.33%
ROI
-35.8%
Units
-1.1
Venue Splits
Mustangs Home
1-0-0 ATS
100% • +89.29%
1-0-0 ML (100%)
Cardinals Home
1-1-0 ATS
50% • -8.33%
2-0-0 ML (100%)
Scoring Averages
Mustangs
75.7
PPG
78.3
allowed
Total
154
Avg
3
games
Cardinals
78.3
PPG
75.7
allowed
Recent Matchups (2025-26)
| Date | Score | ATS | ML | O/U |
|---|---|---|---|---|
| 03/112026-03-11 | L 62-58 | ✓ | L | U |
| 02/172026-02-17 | W 95-85 | ✓ | W | O |
| 01/312026-01-31 | L 88-74 | ✗ | L | U |
Frequently Asked Questions
What is the SMU Mustangs vs Louisville Cardinals all-time record?
The SMU Mustangs are 1-2 against the Louisville Cardinals in 2025-26 in head-to-head matchups.
What is the SMU Mustangs ATS record vs the Louisville Cardinals?
The SMU Mustangs are 2-1-0 against the spread vs the Louisville Cardinals in 2025-26 on DraftKings, with +28.17% ROI.
Do SMU Mustangs vs Louisville Cardinals games go over or under?
SMU Mustangs vs Louisville Cardinals games average 154 total points in 2025-26. The Over has hit 33.33% of the time.

Inside Edge
