Louisville Cardinals Lead SMU Mustangs 3-1 in Head-to-Head Matchups

NCAAB2-2-0 ATS (50%)Data through 2026-03-11

Mustangs vs Cardinals Betting Record

Against the Spread
2-2-0
Win %
50%
ROI
-3.87%
Units
-0.1
Moneyline
1-3-0
Win %
25%
ROI
-35%
Units
-1.4
Over Rate
2-2-0
Win %
50%
ROI
-4.53%
Units
-0.2

From the Other Side — Cardinals vs Mustangs

Against the Spread
2-2-0
Win %
50%
ROI
-6.85%
Units
-0.3
Moneyline
3-1-0
Win %
75%
ROI
+16.04%
Units
+0.6
Over Rate
2-2-0
Win %
50%
ROI
-4.53%
Units
-0.2

Venue Splits

Mustangs Home
1-1-0 ATS
50% • -5.36%
1-1-0 ML (50%)
Cardinals Home
1-1-0 ATS
50% • -8.33%
2-0-0 ML (100%)

Scoring Averages

Mustangs
75
PPG
83.3
allowed
Total
158.3
Avg
4
games
Cardinals
83.3
PPG
75
allowed

Recent Matchups

DateScoreATSMLO/U
03/11L 62-58LU
02/17W 95-85WO
01/31L 88-74LU
01/21L 73-98LO

Frequently Asked Questions

What is the SMU Mustangs vs Louisville Cardinals all-time record?
The SMU Mustangs are 1-3 against the Louisville Cardinals in head-to-head matchups.
What is the SMU Mustangs ATS record vs the Louisville Cardinals?
The SMU Mustangs are 2-2-0 against the spread vs the Louisville Cardinals on DraftKings, with -3.87% ROI.
Do SMU Mustangs vs Louisville Cardinals games go over or under?
SMU Mustangs vs Louisville Cardinals games average 158.3 total points. The Over has hit 50% of the time.

More Mustangs Matchups

Head-to-head betting record for SMU Mustangs vs Louisville Cardinals on LineTerminal. The Mustangs are 1-3 straight up against the Cardinals and 2-2-0 against the spread (50% cover rate, -3.87% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

LineTerminal

AI-powered betting intelligence for NBA, NHL, MLB, and NCAAB.

LineTerminal provides sports data and analytics for informational and entertainment purposes only. LineTerminal does not accept, place, or facilitate bets or wagers of any kind. Odds data is sourced from third-party providers and may not reflect exact lines at every sportsbook. Past performance does not guarantee future results. Sports betting involves risk — never wager more than you can afford to lose.

If you or someone you know has a gambling problem, call 1-800-MY-RESET (National Problem Gambling Helpline) or visit ncpgambling.org. Must be 21+ in most jurisdictions. Please gamble responsibly.

© 2026 LineTerminal. All rights reserved.