Cardinals vs Mustangs Betting Record
Against the Spread
2-2-0
Win %
50%
ROI
-6.85%
Units
-0.3
Moneyline
3-1-0
Win %
75%
ROI
+16.04%
Units
+0.6
Over Rate
2-2-0
Win %
50%
ROI
-4.53%
Units
-0.2
From the Other Side — Mustangs vs Cardinals
Against the Spread
2-2-0
Win %
50%
ROI
-3.87%
Units
-0.1
Moneyline
1-3-0
Win %
25%
ROI
-35%
Units
-1.4
Over Rate
2-2-0
Win %
50%
ROI
-4.53%
Units
-0.2
Venue Splits
Cardinals Home
1-1-0 ATS
50% • -8.33%
2-0-0 ML (100%)
Mustangs Home
1-1-0 ATS
50% • -5.36%
1-1-0 ML (50%)
Scoring Averages
Cardinals
83.3
PPG
75
allowed
Total
158.3
Avg
4
games
Mustangs
75
PPG
83.3
allowed
Recent Matchups
| Date | Score | ATS | ML | O/U |
|---|---|---|---|---|
| 03/112026-03-11 | W 62-58 | ✗ | W | U |
| 02/172026-02-17 | L 95-85 | ✗ | L | O |
| 01/312026-01-31 | W 88-74 | ✓ | W | U |
| 01/212025-01-21 | W 73-98 | ✓ | W | O |
Frequently Asked Questions
What is the Louisville Cardinals vs SMU Mustangs all-time record?
The Louisville Cardinals are 3-1 against the SMU Mustangs in head-to-head matchups.
What is the Louisville Cardinals ATS record vs the SMU Mustangs?
The Louisville Cardinals are 2-2-0 against the spread vs the SMU Mustangs on DraftKings, with -6.85% ROI.
Do Louisville Cardinals vs SMU Mustangs games go over or under?
Louisville Cardinals vs SMU Mustangs games average 158.3 total points. The Over has hit 50% of the time.

Inside Edge
