Cardinals vs Mustangs Betting Record — 2025-26
Against the Spread
1-2-0
Win %
33.33%
ROI
-38.89%
Units
-1.2
Moneyline
2-1-0
Win %
66.67%
ROI
-16.61%
Units
-0.5
Over Rate
1-2-0
Win %
33.33%
ROI
-35.8%
Units
-1.1
From the Other Side — Mustangs vs Cardinals
Against the Spread
2-1-0
Win %
66.67%
ROI
+28.17%
Units
+0.8
Moneyline
1-2-0
Win %
33.33%
ROI
-13.33%
Units
-0.4
Over Rate
1-2-0
Win %
33.33%
ROI
-35.8%
Units
-1.1
Venue Splits
Cardinals Home
1-1-0 ATS
50% • -8.33%
2-0-0 ML (100%)
Mustangs Home
1-0-0 ATS
100% • +89.29%
1-0-0 ML (100%)
Scoring Averages
Cardinals
78.3
PPG
75.7
allowed
Total
154
Avg
3
games
Mustangs
75.7
PPG
78.3
allowed
Recent Matchups (2025-26)
| Date | Score | ATS | ML | O/U |
|---|---|---|---|---|
| 03/112026-03-11 | W 62-58 | ✗ | W | U |
| 02/172026-02-17 | L 95-85 | ✗ | L | O |
| 01/312026-01-31 | W 88-74 | ✓ | W | U |
Frequently Asked Questions
What is the Louisville Cardinals vs SMU Mustangs all-time record?
The Louisville Cardinals are 2-1 against the SMU Mustangs in 2025-26 in head-to-head matchups.
What is the Louisville Cardinals ATS record vs the SMU Mustangs?
The Louisville Cardinals are 1-2-0 against the spread vs the SMU Mustangs in 2025-26 on DraftKings, with -38.89% ROI.
Do Louisville Cardinals vs SMU Mustangs games go over or under?
Louisville Cardinals vs SMU Mustangs games average 154 total points in 2025-26. The Over has hit 33.33% of the time.

Inside Edge
