Notre Dame Fighting Irish Lead Louisville Cardinals 4-2 in Head-to-Head Matchups

NCAAB2-4-0 ATS (33.33%)Data through 2026-02-04

Cardinals vs Fighting Irish Betting Record

Against the Spread
2-4-0
Win %
33.33%
ROI
-36.3%
Units
-2.2
Moneyline
2-4-0
Win %
33.33%
ROI
-61.28%
Units
-3.7
Over Rate
0-5-1
Win %
0%
ROI
-100%
Units
-5.0

From the Other Side — Fighting Irish vs Cardinals

Against the Spread
4-2-0
Win %
66.67%
ROI
+27.62%
Units
+1.7
Moneyline
4-2-0
Win %
66.67%
ROI
+48.86%
Units
+2.9
Over Rate
0-5-1
Win %
0%
ROI
-100%
Units
-5.0

Venue Splits

Cardinals Home
0-3-0 ATS
0% • -100%
1-2-0 ML (33.33%)
Fighting Irish Home
1-2-0 ATS
33.33% • -36.36%
2-1-0 ML (66.67%)

Scoring Averages

Cardinals
65
PPG
69.7
allowed
Total
134.7
Avg
6
games
Fighting Irish
69.7
PPG
65
allowed

Recent Matchups

DateScoreATSMLO/U
02/04W 76-65WU
02/16W 60-75WU
02/21L 50-72LU
01/28L 76-62LP
02/09L 63-57LU
01/22L 70-82LU

Frequently Asked Questions

What is the Louisville Cardinals vs Notre Dame Fighting Irish all-time record?
The Louisville Cardinals are 2-4 against the Notre Dame Fighting Irish in head-to-head matchups.
What is the Louisville Cardinals ATS record vs the Notre Dame Fighting Irish?
The Louisville Cardinals are 2-4-0 against the spread vs the Notre Dame Fighting Irish on DraftKings, with -36.3% ROI.
Do Louisville Cardinals vs Notre Dame Fighting Irish games go over or under?
Louisville Cardinals vs Notre Dame Fighting Irish games average 134.7 total points. The Over has hit 0% of the time.

More Cardinals Matchups

Head-to-head betting record for Louisville Cardinals vs Notre Dame Fighting Irish on LineTerminal. The Cardinals are 2-4 straight up against the Fighting Irish and 2-4-0 against the spread (33.33% cover rate, -36.3% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

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