Fighting Irish vs Cardinals Betting Record
Against the Spread
4-2-0
Win %
66.67%
ROI
+27.62%
Units
+1.7
Moneyline
4-2-0
Win %
66.67%
ROI
+48.86%
Units
+2.9
Over Rate
0-5-1
Win %
0%
ROI
-100%
Units
-5.0
From the Other Side — Cardinals vs Fighting Irish
Against the Spread
2-4-0
Win %
33.33%
ROI
-36.3%
Units
-2.2
Moneyline
2-4-0
Win %
33.33%
ROI
-61.28%
Units
-3.7
Over Rate
0-5-1
Win %
0%
ROI
-100%
Units
-5.0
Venue Splits
Fighting Irish Home
1-2-0 ATS
33.33% • -36.36%
2-1-0 ML (66.67%)
Cardinals Home
0-3-0 ATS
0% • -100%
1-2-0 ML (33.33%)
Scoring Averages
Fighting Irish
69.7
PPG
65
allowed
Total
134.7
Avg
6
games
Cardinals
65
PPG
69.7
allowed
Recent Matchups
| Date | Score | ATS | ML | O/U |
|---|---|---|---|---|
| 02/042026-02-04 | L 76-65 | ✓ | L | U |
| 02/162025-02-16 | L 60-75 | ✗ | L | U |
| 02/212024-02-21 | W 50-72 | ✓ | W | U |
| 01/282023-01-28 | W 76-62 | ✓ | W | P |
| 02/092022-02-09 | W 63-57 | ✗ | W | U |
| 01/222022-01-22 | W 70-82 | ✓ | W | U |
Frequently Asked Questions
What is the Notre Dame Fighting Irish vs Louisville Cardinals all-time record?
The Notre Dame Fighting Irish are 4-2 against the Louisville Cardinals in head-to-head matchups.
What is the Notre Dame Fighting Irish ATS record vs the Louisville Cardinals?
The Notre Dame Fighting Irish are 4-2-0 against the spread vs the Louisville Cardinals on DraftKings, with +27.62% ROI.
Do Notre Dame Fighting Irish vs Louisville Cardinals games go over or under?
Notre Dame Fighting Irish vs Louisville Cardinals games average 134.7 total points. The Over has hit 0% of the time.

Inside Edge
