Twins vs Guardians Betting Record — 2025
Against the Spread
6-7-0
Win %
46.15%
ROI
-27.86%
Units
-3.6
Moneyline
4-9-0
Win %
30.77%
ROI
-37.73%
Units
-4.9
Over Rate
4-8-1
Win %
33.33%
ROI
-34.71%
Units
-4.2
From the Other Side — Guardians vs Twins
Against the Spread
7-6-0
Win %
53.85%
ROI
+5.9%
Units
+0.8
Moneyline
9-4-0
Win %
69.23%
ROI
+30.96%
Units
+4.0
Over Rate
4-8-1
Win %
33.33%
ROI
-34.71%
Units
-4.2
Venue Splits
Twins Home
1-5-0 ATS
16.67% • -72.37%
2-4-0 ML (33.33%)
Guardians Home
2-5-0 ATS
28.57% • -55.17%
5-2-0 ML (71.43%)
Scoring Averages
Twins
3.3
PPG
4.2
allowed
Total
7.5
Avg
13
games
Guardians
4.2
PPG
3.3
allowed
Recent Matchups (2025)
| Date | Score | ATS | ML | O/U |
|---|---|---|---|---|
| 09/212025-09-21 | W 6-2 | ✓ | W | U |
| 09/202025-09-20 | L 0-8 | ✗ | L | U |
| 09/202025-09-20 | L 0-6 | ✗ | L | U |
| 09/192025-09-19 | L 2-6 | ✗ | L | P |
| 08/032025-08-03 | W 4-5 | ✓ | W | O |
| 08/022025-08-02 | L 5-4 | ✓ | L | O |
| 08/012025-08-01 | L 3-2 | ✓ | L | U |
| 05/212025-05-21 | L 1-5 | ✗ | L | U |
| 05/192025-05-19 | W 6-5 | ✗ | W | O |
| 05/012025-05-01 | L 4-3 | ✗ | L | U |
| 04/302025-04-30 | L 4-2 | ✗ | L | U |
| 04/292025-04-29 | L 2-1 | ✓ | L | U |
| 04/282025-04-28 | W 1-11 | ✓ | W | O |
Frequently Asked Questions
What is the Minnesota Twins vs Cleveland Guardians all-time record?
The Minnesota Twins are 4-9 against the Cleveland Guardians in 2025 in head-to-head matchups.
What is the Minnesota Twins ATS record vs the Cleveland Guardians?
The Minnesota Twins are 6-7-0 against the spread vs the Cleveland Guardians in 2025 on DraftKings, with -27.86% ROI.
Do Minnesota Twins vs Cleveland Guardians games go over or under?
Minnesota Twins vs Cleveland Guardians games average 7.5 total points in 2025. The Over has hit 33.33% of the time.

Inside Edge
