Milwaukee Brewers Lead St. Louis Cardinals 7-6 in Head-to-Head Matchups (2025)

MLB5-8-0 ATS (38.46%)Data through 2025-09-21

Brewers vs Cardinals Betting Record — 2025

Against the Spread
5-8-0
Win %
38.46%
ROI
-28.57%
Units
-3.7
Moneyline
7-6-0
Win %
53.85%
ROI
-7.72%
Units
-1.0
Over Rate
5-7-1
Win %
41.67%
ROI
-20.59%
Units
-2.5

From the Other Side — Cardinals vs Brewers

Against the Spread
8-5-0
Win %
61.54%
ROI
+0.92%
Units
+0.1
Moneyline
6-7-0
Win %
46.15%
ROI
-5.12%
Units
-0.7
Over Rate
5-7-1
Win %
41.67%
ROI
-20.59%
Units
-2.5

Venue Splits

Brewers Home
2-5-0 ATS
28.57% • -48.25%
5-2-0 ML (71.43%)
Cardinals Home
3-3-0 ATS
50% • -16.41%
4-2-0 ML (66.67%)

Scoring Averages

Brewers
4.2
PPG
3.8
allowed
Total
8
Avg
13
games
Cardinals
3.8
PPG
4.2
allowed

Recent Matchups (2025)

DateScoreATSMLO/U
09/21L 5-1LU
09/20W 2-3WU
09/19L 7-1LO
09/14L 2-3LU
09/13W 9-8WO
09/12W 8-2WO
06/15W 3-2WU
06/14L 5-8LO
06/13W 3-2WU
06/12W 6-0WU
04/27W 1-7WP
04/26L 6-5LO
04/25L 3-2LU

Frequently Asked Questions

What is the Milwaukee Brewers vs St. Louis Cardinals all-time record?
The Milwaukee Brewers are 7-6 against the St. Louis Cardinals in 2025 in head-to-head matchups.
What is the Milwaukee Brewers ATS record vs the St. Louis Cardinals?
The Milwaukee Brewers are 5-8-0 against the spread vs the St. Louis Cardinals in 2025 on DraftKings, with -28.57% ROI.
Do Milwaukee Brewers vs St. Louis Cardinals games go over or under?
Milwaukee Brewers vs St. Louis Cardinals games average 8 total points in 2025. The Over has hit 41.67% of the time.

More Brewers Matchups

Head-to-head betting record for Milwaukee Brewers vs St. Louis Cardinals in the 2025 season on LineTerminal. The Brewers are 7-6 straight up against the Cardinals and 5-8-0 against the spread (38.46% cover rate, -28.57% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

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