Milwaukee Brewers Lead St. Louis Cardinals 43-40 in Head-to-Head Matchups

MLB33-38-0 ATS (46.48%)Data through 2025-09-21

Brewers vs Cardinals Betting Record

Against the Spread
33-38-0
Win %
46.48%
ROI
-5.23%
Units
-3.7
Moneyline
43-39-1
Win %
52.44%
ROI
-4.41%
Units
-3.6
Over Rate
29-40-2
Win %
42.03%
ROI
-19.88%
Units
-13.7

From the Other Side — Cardinals vs Brewers

Against the Spread
38-33-0
Win %
53.52%
ROI
-6.73%
Units
-4.8
Moneyline
39-43-1
Win %
47.56%
ROI
-0.42%
Units
-0.3
Over Rate
29-40-2
Win %
42.03%
ROI
-19.88%
Units
-13.7

Venue Splits

Brewers Home
17-20-0 ATS
45.95% • -4.31%
23-20-1 ML (53.49%)
Cardinals Home
18-16-0 ATS
52.94% • -7.96%
19-20-0 ML (48.72%)

Scoring Averages

Brewers
4
PPG
3.8
allowed
Total
7.7
Avg
83
games
Cardinals
3.8
PPG
4
allowed

Recent Matchups

DateScoreATSMLO/U
09/21L 5-1LU
09/20W 2-3WU
09/19L 7-1LO
09/14L 2-3LU
09/13W 9-8WO
09/12W 8-2WO
06/15W 3-2WU
06/14L 5-8LO
06/13W 3-2WU
06/12W 6-0WU
04/27W 1-7WP
04/26L 6-5LO
04/25L 3-2LU
09/04L 2-3LU
09/03L 4-7LO
09/02W 9-3WO
08/22L 3-0LU
08/21L 10-6LO
08/20W 2-3WU
05/12L 3-4LU

Frequently Asked Questions

What is the Milwaukee Brewers vs St. Louis Cardinals all-time record?
The Milwaukee Brewers are 43-40 against the St. Louis Cardinals in head-to-head matchups.
What is the Milwaukee Brewers ATS record vs the St. Louis Cardinals?
The Milwaukee Brewers are 33-38-0 against the spread vs the St. Louis Cardinals on DraftKings, with -5.23% ROI.
Do Milwaukee Brewers vs St. Louis Cardinals games go over or under?
Milwaukee Brewers vs St. Louis Cardinals games average 7.7 total points. The Over has hit 42.03% of the time.

More Brewers Matchups

Head-to-head betting record for Milwaukee Brewers vs St. Louis Cardinals on LineTerminal. The Brewers are 43-40 straight up against the Cardinals and 33-38-0 against the spread (46.48% cover rate, -5.23% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

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