Seattle Mariners Lead Houston Astros 8-5 in Head-to-Head Matchups (2025)

MLB7-6-0 ATS (53.85%)Data through 2025-09-21

Astros vs Mariners Betting Record — 2025

Against the Spread
7-6-0
Win %
53.85%
ROI
-15.44%
Units
-2.0
Moneyline
5-8-0
Win %
38.46%
ROI
-18.75%
Units
-2.4
Over Rate
6-5-2
Win %
54.55%
ROI
+5.22%
Units
+0.6

From the Other Side — Mariners vs Astros

Against the Spread
6-7-0
Win %
46.15%
ROI
+6.42%
Units
+0.8
Moneyline
8-5-0
Win %
61.54%
ROI
+12.56%
Units
+1.6
Over Rate
6-5-2
Win %
54.55%
ROI
+5.22%
Units
+0.6

Venue Splits

Astros Home
3-4-0 ATS
42.86% • -29.41%
3-4-0 ML (42.86%)
Mariners Home
2-4-0 ATS
33.33% • -31.08%
4-2-0 ML (66.67%)

Scoring Averages

Astros
4.2
PPG
4.3
allowed
Total
8.5
Avg
13
games
Mariners
4.3
PPG
4.2
allowed

Recent Matchups (2025)

DateScoreATSMLO/U
09/21L 3-7LO
09/20L 4-6LO
09/19L 0-4LU
07/20W 3-11WO
07/19L 7-6LO
07/18L 6-1LP
05/25W 5-3WU
05/24W 2-1WU
05/23L 3-5LU
05/22W 9-2WO
04/09L 7-6LO
04/08W 1-2WU
04/07L 4-3LP

Frequently Asked Questions

What is the Houston Astros vs Seattle Mariners all-time record?
The Houston Astros are 5-8 against the Seattle Mariners in 2025 in head-to-head matchups.
What is the Houston Astros ATS record vs the Seattle Mariners?
The Houston Astros are 7-6-0 against the spread vs the Seattle Mariners in 2025 on DraftKings, with -15.44% ROI.
Do Houston Astros vs Seattle Mariners games go over or under?
Houston Astros vs Seattle Mariners games average 8.5 total points in 2025. The Over has hit 54.55% of the time.

More Astros Matchups

Head-to-head betting record for Houston Astros vs Seattle Mariners in the 2025 season on LineTerminal. The Astros are 5-8 straight up against the Mariners and 7-6-0 against the spread (53.85% cover rate, -15.44% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

LineTerminal

AI-powered betting intelligence for NBA, NHL, MLB, and NCAAB.

LineTerminal provides sports data and analytics for informational and entertainment purposes only. LineTerminal does not accept, place, or facilitate bets or wagers of any kind. Odds data is sourced from third-party providers and may not reflect exact lines at every sportsbook. Past performance does not guarantee future results. Sports betting involves risk — never wager more than you can afford to lose.

If you or someone you know has a gambling problem, call 1-800-MY-RESET (National Problem Gambling Helpline) or visit ncpgambling.org. Must be 21+ in most jurisdictions. Please gamble responsibly.

© 2026 LineTerminal. All rights reserved.