Astros vs Mariners Betting Record
Against the Spread
30-42-0
Win %
41.67%
ROI
-18.4%
Units
-13.3
Moneyline
47-42-0
Win %
52.81%
ROI
-9.87%
Units
-8.8
Over Rate
33-35-4
Win %
48.53%
ROI
-7.69%
Units
-5.2
From the Other Side — Mariners vs Astros
Against the Spread
42-30-0
Win %
58.33%
ROI
+10.23%
Units
+7.4
Moneyline
42-47-0
Win %
47.19%
ROI
+0.54%
Units
+0.5
Over Rate
33-35-4
Win %
48.53%
ROI
-7.69%
Units
-5.2
Venue Splits
Astros Home
14-24-0 ATS
36.84% • -26%
28-21-0 ML (57.14%)
Mariners Home
18-16-0 ATS
52.94% • +0.03%
21-19-0 ML (52.5%)
Scoring Averages
Astros
4.2
PPG
3.9
allowed
Total
8.1
Avg
89
games
Mariners
3.9
PPG
4.2
allowed
Recent Matchups
| Date | Score | ATS | ML | O/U |
|---|---|---|---|---|
| 09/212025-09-21 | L 3-7 | ✗ | L | O |
| 09/202025-09-20 | L 4-6 | ✗ | L | O |
| 09/192025-09-19 | L 0-4 | ✗ | L | U |
| 07/202025-07-20 | W 3-11 | ✓ | W | O |
| 07/192025-07-19 | L 7-6 | ✓ | L | O |
| 07/182025-07-18 | L 6-1 | ✗ | L | P |
| 05/252025-05-25 | W 5-3 | ✓ | W | U |
| 05/242025-05-24 | W 2-1 | ✓ | W | U |
| 05/232025-05-23 | L 3-5 | ✗ | L | U |
| 05/222025-05-22 | W 9-2 | ✓ | W | O |
| 04/092025-04-09 | L 7-6 | ✗ | L | O |
| 04/082025-04-08 | W 1-2 | ✓ | W | U |
| 04/072025-04-07 | L 4-3 | ✓ | L | P |
| 09/252024-09-25 | L 1-8 | ✗ | L | O |
| 09/242024-09-24 | W 4-3 | ✗ | W | P |
| 09/232024-09-23 | L 1-6 | ✗ | L | U |
| 07/212024-07-21 | L 6-4 | ✗ | L | O |
| 07/202024-07-20 | W 2-4 | ✓ | W | U |
| 07/192024-07-19 | W 0-3 | ✓ | W | U |
| 05/302024-05-30 | W 0-4 | ✓ | W | U |
Frequently Asked Questions
What is the Houston Astros vs Seattle Mariners all-time record?
The Houston Astros are 47-42 against the Seattle Mariners in head-to-head matchups.
What is the Houston Astros ATS record vs the Seattle Mariners?
The Houston Astros are 30-42-0 against the spread vs the Seattle Mariners on DraftKings, with -18.4% ROI.
Do Houston Astros vs Seattle Mariners games go over or under?
Houston Astros vs Seattle Mariners games average 8.1 total points. The Over has hit 48.53% of the time.

Inside Edge
