Houston Astros Lead Seattle Mariners 47-42 in Head-to-Head Matchups

MLB30-42-0 ATS (41.67%)Data through 2025-09-21

Astros vs Mariners Betting Record

Against the Spread
30-42-0
Win %
41.67%
ROI
-18.4%
Units
-13.3
Moneyline
47-42-0
Win %
52.81%
ROI
-9.87%
Units
-8.8
Over Rate
33-35-4
Win %
48.53%
ROI
-7.69%
Units
-5.2

From the Other Side — Mariners vs Astros

Against the Spread
42-30-0
Win %
58.33%
ROI
+10.23%
Units
+7.4
Moneyline
42-47-0
Win %
47.19%
ROI
+0.54%
Units
+0.5
Over Rate
33-35-4
Win %
48.53%
ROI
-7.69%
Units
-5.2

Venue Splits

Astros Home
14-24-0 ATS
36.84% • -26%
28-21-0 ML (57.14%)
Mariners Home
18-16-0 ATS
52.94% • +0.03%
21-19-0 ML (52.5%)

Scoring Averages

Astros
4.2
PPG
3.9
allowed
Total
8.1
Avg
89
games
Mariners
3.9
PPG
4.2
allowed

Recent Matchups

DateScoreATSMLO/U
09/21L 3-7LO
09/20L 4-6LO
09/19L 0-4LU
07/20W 3-11WO
07/19L 7-6LO
07/18L 6-1LP
05/25W 5-3WU
05/24W 2-1WU
05/23L 3-5LU
05/22W 9-2WO
04/09L 7-6LO
04/08W 1-2WU
04/07L 4-3LP
09/25L 1-8LO
09/24W 4-3WP
09/23L 1-6LU
07/21L 6-4LO
07/20W 2-4WU
07/19W 0-3WU
05/30W 0-4WU

Frequently Asked Questions

What is the Houston Astros vs Seattle Mariners all-time record?
The Houston Astros are 47-42 against the Seattle Mariners in head-to-head matchups.
What is the Houston Astros ATS record vs the Seattle Mariners?
The Houston Astros are 30-42-0 against the spread vs the Seattle Mariners on DraftKings, with -18.4% ROI.
Do Houston Astros vs Seattle Mariners games go over or under?
Houston Astros vs Seattle Mariners games average 8.1 total points. The Over has hit 48.53% of the time.

More Astros Matchups

Head-to-head betting record for Houston Astros vs Seattle Mariners on LineTerminal. The Astros are 47-42 straight up against the Mariners and 30-42-0 against the spread (41.67% cover rate, -18.4% ROI) on DraftKings. Data sourced from DraftKings closing lines. Updated daily after games are graded. Past performance does not guarantee future results.

LineTerminal

AI-powered betting intelligence for NBA, NHL, MLB, and NCAAB.

LineTerminal provides sports data and analytics for informational and entertainment purposes only. LineTerminal does not accept, place, or facilitate bets or wagers of any kind. Odds data is sourced from third-party providers and may not reflect exact lines at every sportsbook. Past performance does not guarantee future results. Sports betting involves risk — never wager more than you can afford to lose.

If you or someone you know has a gambling problem, call 1-800-MY-RESET (National Problem Gambling Helpline) or visit ncpgambling.org. Must be 21+ in most jurisdictions. Please gamble responsibly.

© 2026 LineTerminal. All rights reserved.